Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | RRM1 | P23921 | 2/20 | 0.30 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14969297 | 0.84 | ACLY (0.36) | CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL14969189 | 0.81 | IKBKB (0.35) | — | |
| SCHEMBL14969048 | 0.77 | SLC1A3 (0.38) | — | |
| SCHEMBL14969233 | 0.71 | IKBKB (0.40) | — | |
| SCHEMBL14969015 | 0.68 | KDM4E (0.39) | — | |
| SCHEMBL7908992 | 0.66 | GSTO1 (0.45) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14968966 | 0.63 | IKBKB (0.41) | — | |
| SCHEMBL14969185 | 0.60 | RCE1 (0.38) | — | |
| SCHEMBL8212413 | 0.59 | LMNA (0.49) | CA12CA1CA2CA3CA4 | |
| SCHEMBL8560217 | 0.59 | CSNK1A1 (0.41) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |