Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 14/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23801088 | 0.86 | ALDH1A1 (0.41) | PDK2THRBTDP1ALDH1A1TSHR | |
| SCHEMBL23996967 | 0.84 | PDK2 (0.47) | PDK2THRBTDP1ALDH1A1ALOX12 | |
| SCHEMBL14970802 | 0.81 | PDK2 (0.46) | PDK2THRBTDP1ALDH1A1HSP90AA1 | |
| SCHEMBL22876001 | 0.80 | SLC6A3 (0.45) | PDK2THRBTDP1ALDH1A1TSHR | |
| SCHEMBL4822724 | 0.79 | SLC6A3 (0.41) | PDK2THRBTDP1ALDH1A1TSHR | |
| SCHEMBL15498008 | 0.77 | CYP3A4 (0.36) | PDK2TDP1ALDH1A1TSHRALOX12 | |
| SCHEMBL15498007 | 0.77 | CYP3A4 (0.36) | PDK2TDP1ALDH1A1TSHRALOX12 | |
| SCHEMBL15498009 | 0.77 | CYP3A4 (0.36) | PDK2TDP1ALDH1A1TSHRALOX12 | |
| SCHEMBL12390765 | 0.77 | CRHBP (0.47) | PDK2THRBTDP1ALDH1A1TSHR | |
| SCHEMBL19039047 | 0.75 | PDK2 (0.50) | PDK2THRBTDP1ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210388216-A1 | Crosslinked Aromatic Polymer Compositions and Methods of Making Insulation Coatings For Use on Components Subject to High Temperature, Corrosive and/or High Voltage End Applications | GREENE, TWEED TECHNOLOGIES, INC. | 2021-12-16 | — | — | US | disclosed |
| WO-2021242672-A1 | CROSSLINKED AROMATIC POLYMER COMPOSITIONS AND METHODS OF MAKING INSULATION COATINGS | GREENE, TWEED TECHNOLOGIES, INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| EP-3916035-A1 | METHOD FOR CONTROLLING CROSS-LINKING REACTION RATE AND OF A CROSS-LINKING COMPOUND | Delsper LP (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-2909253-B1 | CROSS-LINKED ORGANIC POLYMER COMPOSITIONS | Delsper LP (US) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020056052-A1 | CROSSLINKABLE AROMATIC POLYMER COMPOSITIONS FOR USE IN ADDITIVE MANUFACTURING PROCESSES AND METHODS FOR FORMING THE SAME | GREENE, TWEED TECHNOLOGIES, INC. (US) | 2020-03-19 | — | — | WO | disclosed |
| US-20170183445-A1 | Anti-Extrusion Compositions for Sealing and Wear Components | Delsper LP | 2017-06-29 | — | — | US | disclosed |
| US-20170183445-A1 | Anti-Extrusion Compositions for Sealing and Wear Components | Delsper LP | 2017-06-29 | — | — | US | disclosed |
| US-9475938-B2 | Anti-extrusion compositions for sealing and wear components | DELSPER, LP (US) | 2016-10-25 | — | — | US | disclosed |
| US-9475938-B2 | Anti-extrusion compositions for sealing and wear components | DELSPER, LP (US) | 2016-10-25 | — | — | US | disclosed |
| EP-2780392-B1 | CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS | GREENE TWEED & CO INC (US) | 2016-06-29 | — | — | EP | disclosed |
| US-20140323668-A1 | CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS | GREENE, TWEED & CO. (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140316079-A1 | Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications | Delsper LP | 2014-10-23 | — | — | US | disclosed |
| US-20140316079-A1 | Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications | Delsper LP | 2014-10-23 | — | — | US | disclosed |
| US-20140284850-A1 | Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability | Delsper LP | 2014-09-25 | — | — | US | disclosed |
| US-20140284850-A1 | Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability | Delsper LP | 2014-09-25 | — | — | US | disclosed |
| WO-2014145834-A1 | CROSS-LINKED ORGANIC POLYMERS FOR USE AS ELASTOMERS | Delsper LP (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014066268-A9 | CROSS-LINKED ORGANIC POLYMER COMPOSITIONS | GREENE, TWEED OF DELAWARE, INC. (US) | 2014-08-14 | — | — | WO | disclosed |
| US-20140213742-A1 | Anti-Extrusion Compositions for Sealing and Wear Components | Delsper LP (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140213742-A1 | Anti-Extrusion Compositions for Sealing and Wear Components | Delsper LP (US) | 2014-07-31 | — | — | US | disclosed |
| WO-2013074120-A1 | CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS | GREENE, TWEED & CO. (US) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140284850-A1 | Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability | AOX1, DUOX2, HAO2 | PDK2 890/4885THRB 4511/4885TDP1 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.