Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloguanil SCHEMBL140230 | 0.90 | DHFR (1.00) | DHFRLMNA | |
| Cycloguanil SCHEMBL2700759 | 0.89 | DHFR (0.97) | DHFRLMNA | |
| Cycloguanil SCHEMBL1649173 | 0.87 | DHFR (0.94) | DHFRLMNA | |
| Cycloguanil SCHEMBL9246965 | 0.83 | DHFR (0.86) | DHFR | |
| SCHEMBL670640 | 0.81 | DHFR (0.49) | DHFRLMNA | |
| SCHEMBL4104810 | 0.76 | DHFR (0.73) | DHFRLMNA | |
| SCHEMBL4103257 | 0.75 | DHFR (0.71) | DHFRLMNA | |
| SCHEMBL1938185 | 0.75 | DHFR (1.00) | DHFRLMNA | |
| Chlorcycloguanil SCHEMBL8986158 | 0.74 | DHFR (1.00) | DHFR | |
| SCHEMBL669914 | 0.74 | DHFR (0.77) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11844802-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2023-12-19 | — | — | US | disclosed |
| US-20230044670-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | UNIV EMORY (US) | 2023-02-09 | — | — | US | disclosed |
| US-20210100806-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | UNIV EMORY (US) | 2021-04-08 | — | — | US | disclosed |
| US-10888565-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2021-01-12 | — | — | US | disclosed |
| US-20200121687-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | UNIV EMORY (US) | 2020-04-23 | — | — | US | disclosed |
| US-20180207166-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-07-26 | — | — | US | disclosed |
| EP-3187197-A1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | Emory University (US) | 2017-07-05 | — | — | EP | disclosed |
| EP-2605804-B1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | UNIV EMORY (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9511071-B2 | Compounds and compositions for ossification and methods related thereto | EMORY UNIVERSITY (US) | 2016-12-06 | — | — | US | disclosed |
| US-20130137634-A1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10888565-B2 | Compounds and compositions for ossification and methods related thereto | BMP2, SOST, BMP4 | DHFR 3180/4885LMNA 3954/4885 |
| US-20130137634-A1 | COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO | BMP2, SOST, BMP4 | DHFR 3180/4885LMNA 3954/4885 |
| US-20180207166-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | DHFR 3180/4885LMNA 3954/4885 |
| US-20230044670-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | DHFR 3180/4885LMNA 3954/4885 |
| US-20210100806-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | DHFR 3180/4885LMNA 3954/4885 |
| US-20200121687-A1 | Compounds and Compositions for Ossification and Methods Related Thereto | BMP2, SOST, BMP4 | DHFR 3180/4885LMNA 3954/4885 |
| US-11844802-B2 | Compounds and compositions for ossification and methods related thereto | BMP2, SOST, BMP4 | DHFR 3180/4885LMNA 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.