Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.97 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104810 | 0.84 | DHFR (0.73) | DHFRLMNA | |
| SCHEMBL16102719 | 0.84 | PPP3CB (1.00) | DHFRLMNAPPP3CB | |
| Cycloguanil SCHEMBL140230 | 0.83 | DHFR (1.00) | DHFRLMNA | |
| SCHEMBL4103257 | 0.83 | DHFR (0.71) | DHFRLMNA | |
| SCHEMBL14577695 | 0.82 | DHFR (0.72) | DHFRLMNA | |
| Cycloguanil SCHEMBL2700759 | 0.81 | DHFR (0.97) | DHFRLMNA | |
| Hydrochloric Acid SCHEMBL6369976 | 0.81 | DHFR (0.70) | DHFRLMNA | |
| SCHEMBL670885 | 0.81 | DHFR (1.00) | DHFR | |
| SCHEMBL14577798 | 0.81 | DHFR (1.00) | DHFRLMNA | |
| SCHEMBL14577705 | 0.81 | DHFR (0.70) | DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110087609-B | Water-in-oil emulsion containing baicalin, xanthine base, vitamin B3, and polyvalent metal cation salt | 莱雅公司 | 2022-11-15 | — | — | CN | disclosed |
| EP-3131883-B1 | 5-HT2B ANTAGONISTS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2018-06-13 | — | — | EP | disclosed |
| US-20180111908-A1 | 5-HT2B Antagonists | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-04-26 | — | — | US | disclosed |
| US-9845298-B1 | 5-HT2B antagonists | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2017-12-19 | — | — | US | disclosed |
| US-20170349559-A1 | 5-HT2B Antagonists | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2017-12-07 | — | — | US | disclosed |
| EP-1574503-B1 | 2,4-Diamino-1,3,5-triazine derivative | HAMARI CHEMICALS LTD (JP) | 2013-03-13 | — | — | EP | disclosed |
| US-20110207926-A1 | NOVEL DIHYDROTRIAZINE DERIVATIVE | HAMARI CHEMICALS, LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2332925-A1 | NOVEL DIHYDROTRIAZINE DERIVATIVE | Hamari Chemicals, Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-7947701-B2 | Dual molecules containing peroxy derivative, the synthesis and therapeutic applications thereof | SANOFI-AVENTIS (FR) | 2011-05-24 | — | — | US | disclosed |
| US-7622469-B2 | 2,4-diamino-1,3,5-triazine derivatives | HAMARI CHEMICALS, LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-7566710-B2 | Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof | Centre National de la Racherche Scientifique (C.N.R.S.) (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20070021423-A1 | Dual molecules containing peroxy derivative, the synthesis and therapeutic applications thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-01-25 | — | — | US | disclosed |
| US-20060154928-A1 | Novel 2,4-diamino-1,3,5-triazine derivative | HAMARI CHEMICALS, LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1574503-A1 | NOVEL 2,4-DIAMINO-1,3,5-TRIAZINE DERIVATIVE | Hamari Chemicals Co., Ltd. (JP) | 2005-09-14 | — | — | EP | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111908-A1 | 5-HT2B Antagonists | HTR2B, HTR5A, VIPR2 | DHFR 2635/4885LMNA 1479/4885PPP3CB 1161/4885 |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | DHFR 1710/4885LMNA 117/4885PPP3CB 4835/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | DHFR 2438/4885LMNA 132/4885PPP3CB 4408/4885 |
| US-20070021423-A1 | Dual molecules containing peroxy derivative, the synthesis and therapeutic applications thereof | PRDX2, PRDX1, PRDX5 | DHFR 124/4885LMNA 2822/4885PPP3CB 476/4885 |
| US-20170349559-A1 | 5-HT2B Antagonists | HTR2B, HTR5A, VIPR2 | DHFR 2635/4885LMNA 1479/4885PPP3CB 1161/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | DHFR 2941/4885LMNA 85/4885PPP3CB 4611/4885 |
| US-20060154928-A1 | Novel 2,4-diamino-1,3,5-triazine derivative | DAZAP1, DCUN1D5, TLR5 | DHFR 809/4885LMNA 4829/4885PPP3CB 3527/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | DHFR 642/4885LMNA 129/4885PPP3CB 4734/4885 |
| US-20110207926-A1 | NOVEL DIHYDROTRIAZINE DERIVATIVE | QDPR, DRD4, DRD1 | DHFR 38/4885LMNA 3250/4885PPP3CB 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.