Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | GAA | P10253 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692132 | 0.77 | TDO2 (0.38) | MAPTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL4482096 | 0.77 | TDO2 (0.38) | MAPTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL247757 | 0.77 | TDO2 (0.38) | MAPTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL28273169 | 0.77 | KDM4E (0.36) | MAPTGAAKDM4EALDH1A1ALOX15 | |
| SCHEMBL1498644 | 0.75 | PDE5A (0.38) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL1498733 | 0.74 | KDM4E (0.34) | MAPTGAAKDM4EALOX15HDAC3 | |
| SCHEMBL3963851 | 0.74 | GAA (0.53) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL3688474 | 0.73 | ALOX15 (0.37) | MAPTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL1498651 | 0.73 | KCNH3 (0.46) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL990901 | 0.72 | MAPT (0.47) | MAPTGAAKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506452-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |