Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498733 | 0.85 | KDM4E (0.34) | ALOX15 | |
| SCHEMBL1498738 | 0.80 | IDO1 (0.35) | ALOX15ALDH1A1 | |
| SCHEMBL28273169 | 0.76 | KDM4E (0.36) | ALOX15ALDH1A1 | |
| SCHEMBL3688474 | 0.75 | ALOX15 (0.37) | ALOX15ALDH1A1 | |
| SCHEMBL3692132 | 0.73 | TDO2 (0.38) | ALDH1A1 | |
| SCHEMBL4482096 | 0.73 | TDO2 (0.38) | ALDH1A1 | |
| SCHEMBL247757 | 0.73 | TDO2 (0.38) | ALDH1A1 | |
| SCHEMBL1498815 | 0.70 | TLR8 (0.37) | ALOX15 | |
| SCHEMBL1498710 | 0.69 | CNR1 (0.38) | ALDH1A1 | |
| SCHEMBL1498685 | 0.68 | MAPT (0.44) | ALOX15ALDH1A1CYP3A4ALOX12MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240559-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | Chemtura Corporation (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009076090-A2 | CYCLOALKYL PHENYLENEDIAMINES AS DEPOSIT CONTROL AGENTS FOR LUBRICANTS | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |