Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL5287077 | 0.91 | ALDH1A1 (0.47) | PTGS2CES2CES1ALDH1A1TSHR | |
| Styrene SCHEMBL11565626 | 0.88 | ALDH1A1 (0.44) | PTGS2CES2CES1ALDH1A1TSHR | |
| SCHEMBL26185780 | 0.86 | TAS1R3 (0.44) | PTGS2CES2CES1ALDH1A1ESR1 | |
| SCHEMBL28429904 | 0.86 | THRA (0.46) | PTGS2CES2CES1ALDH1A1HPGD | |
| SCHEMBL1503077 | 0.84 | ALDH1A1 (0.42) | PTGS2CES2CES1ALDH1A1CYP3A4 | |
| Styrene SCHEMBL9765284 | 0.84 | CES2 (0.46) | PTGS2CES2CES1ALDH1A1TSHR | |
| Styrene SCHEMBL14058497 | 0.83 | PTGS2 (0.40) | PTGS2CES2CES1ALDH1A1TSHR | |
| SCHEMBL20448 | 0.82 | PTGS2 (0.57) | PTGS2CES2CES1ALDH1A1ESR1 | |
| SCHEMBL9715780 | 0.81 | TAS1R3 (0.43) | CES2CES1ALDH1A1MEN1KMT2A | |
| Styrene SCHEMBL27084529 | 0.81 | ALDH1A1 (0.50) | PTGS2CES2CES1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988873-B1 | POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME | LUBRIZOL ADVANCED MAT INC (US) | 2013-01-09 | — | — | EP | claimed |
| US-8021650-B2 | Polymers containing silicone copolyol macromers and personal care compositions containing same | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2011-09-20 | — | — | US | claimed |
| EP-1988873-A2 | POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME | Lubrizol Advanced Materials, Inc. (US) | 2008-11-12 | — | — | EP | claimed |
| WO-2007101059-A2 | POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070202069-A1 | Polymers Containing Silicone Copolyol Macromers and Personal Care Compositions Containing Same | LUBRIZOL ADVANCED MATERIALS, INC. | 2007-08-30 | — | — | US | claimed |
| US-5053151-A | Ethylene-alpha-olefin copolymer grafted with unsaturated carboxy compound | EXXON CHEMICAL PATENTS INC. (US) | 1991-10-01 | — | — | US | disclosed |