Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385858 | 0.91 | GABRA1 (0.48) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL16736689 | 0.86 | GABRA1 (0.48) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL6643213 | 0.82 | ACHE (0.46) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL5002736 | 0.81 | GABRA1 (0.48) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL31017692 | 0.79 | GABRA1 (0.44) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL11048642 | 0.79 | GABRA1 (0.44) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL1335807 | 0.79 | GABRA1 (0.48) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL5530284 | 0.77 | GABRA1 (0.45) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL16736711 | 0.77 | ALOX15 (0.41) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL1493936 | 0.77 | POLB (0.49) | GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306630-A1 | AGONISTS OF ROR GAMMAt | BRISTOL MYERS SQUIBB CO (US) | 2022-09-29 | — | — | US | disclosed |
| US-9161945-B2 | 4-isopropyl-6-methoxyphenyl glucitol compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-10-20 | — | — | US | disclosed |
| EP-2607360-B1 | 4-Isopropyl-6-methoxyphenyl glucitol compound | TAISHO PHARMACEUTICAL CO LTD (JP) | 2015-08-19 | — | — | EP | disclosed |
| US-20130165645-A1 | 4-ISOPROPYL-6-METHOXYPHENYL GLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2013-06-27 | — | — | US | disclosed |
| EP-2607360-A1 | 4-ISOPROPYL-6-METHOXYPHENYL GLUCITOL COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-06-26 | — | — | EP | disclosed |
| US-8466113-B2 | 4-isopropylphenyl glucitol compounds as SGLT1 inhibitors | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20110306759-A1 | 4-ISOPROPYLPHENYL GLUCITOL COMPOUNDS AS SGLT1 INHIBITORS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165645-A1 | 4-ISOPROPYL-6-METHOXYPHENYL GLUCITOL COMPOUND | SLC5A1, SLC5A2, SLC2A4 | GABRA1 2128/4885GABRB1 1517/4885CA1 4169/4885 |
| US-20110306759-A1 | 4-ISOPROPYLPHENYL GLUCITOL COMPOUNDS AS SGLT1 INHIBITORS | SLC5A1, SLC5A2, SLC2A4 | GABRA1 2173/4885GABRB1 1584/4885CA1 3112/4885 |
| US-20220306630-A1 | AGONISTS OF ROR GAMMAt | RORB, RORA, RORC | GABRA1 145/4885GABRB1 135/4885CA1 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.