Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503228 | 0.81 | MAOB (0.43) | MAOBMAPT | |
| SCHEMBL4304552 | 0.78 | KDM5A (0.40) | MAOBPIK3CAHDAC3HDAC1HDAC2 | |
| Acetic Acid SCHEMBL27812979 | 0.76 | MAOB (0.41) | MAOBMAPTXDHSLC22A12 | |
| SCHEMBL1503109 | 0.76 | HDAC1 (0.47) | MAOBPIK3CAHDAC3HDAC1HDAC2 | |
| SCHEMBL1503279 | 0.73 | L3MBTL1 (0.36) | KDM4EL3MBTL1 | |
| SCHEMBL27833091 | 0.71 | KDM5A (0.39) | MAOBPIK3CAHDAC3HDAC1HDAC2 | |
| SCHEMBL27833092 | 0.68 | RNASEH1 (0.38) | MAOBPIK3CAHDAC3HDAC1HDAC2 | |
| SCHEMBL30954800 | 0.67 | DAO (0.39) | MAOBMAPT | |
| SCHEMBL2195620 | 0.67 | PIK3CA (0.47) | PIK3CAHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL30954801 | 0.66 | PTGS1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300433-A1 | HIV INTEGRASE INHIBITORS FROM PYRIDOXINE | Ambrilia Biopharma Inc. (CA) | 2011-03-30 | — | — | EP | claimed |