SCHEMBL15034016

SCHEMBL15034016

FC(F)(F)c1cccc(N2COc3c(ccc4cccnc34)C2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
MAPT P10636 5/20 0.48
TP53 P04637 3/20 0.48
PHGDH O43175 4/20 0.47
HTR2C P28335 3/20 0.42
HTR2A P28223 2/20 0.42
HTR7 P34969 2/20 0.42
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR1D P28221 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
SLC40A1 Q9NP59 1/20 0.39
DHFR P00374 1/20 0.39
THRB P10828 1/20 0.38
KDM4E B2RXH2 3/20 0.38
POLB P06746 2/20 0.38
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12011964 0.82 SLC40A1 (0.45) ALDH1A1MAPTTP53HTR2CHTR2A
SCHEMBL765719 0.81 GLO1 (0.35) MAPTTP53SLC40A1KDM4EHSP90AA1
SCHEMBL5958802 0.80 ALDH1A1 (0.58) ALDH1A1MAPTTP53HTR2CHTR7
SCHEMBL10045025 0.79 SLC40A1 (0.38) ALDH1A1MAPTTP53SLC40A1KDM4E
SCHEMBL10311139 0.79 KDM4E (0.39) ALDH1A1MAPTTP53HTR2CHTR2A
SCHEMBL16381563 0.78 RXRA (0.36) MAPTSLC40A1KDM4EHTTSMN1; SMN2
SCHEMBL10044970 0.77 LMNA (0.42) ALDH1A1MAPTTP53HTR2CHTR2A
SCHEMBL5958800 0.77 ALDH1A1 (0.49) ALDH1A1MAPTPHGDHHTR2CHTR3E
SCHEMBL10311145 0.74 ALDH1A1 (0.51) ALDH1A1MAPTTP53PHGDHHTR2C
SCHEMBL10311138 0.74 ALDH1A1 (0.45) ALDH1A1MAPTTP53SLC40A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355284-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-16 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-20130157168-A1 COMPOSITION, COMPOSITE PREPARED FROM THE COMPOSITION, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL EACH INCLUDING THE SAME, METHOD OF PREPARING THE ELECTROLYTE MEMBRANE, AND FUEL CELL INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-06-20 US disclosed
US-20130157168-A1 COMPOSITION, COMPOSITE PREPARED FROM THE COMPOSITION, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL EACH INCLUDING THE SAME, METHOD OF PREPARING THE ELECTROLYTE MEMBRANE, AND FUEL CELL INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-06-20 US disclosed