SCHEMBL765719

SCHEMBL765719

Fc1ccc(N2COc3c(ccc4cccnc34)C2)cc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.35
MAPT P10636 3/20 0.34
KDM4E B2RXH2 3/20 0.34
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
GAA P10253 1/20 0.34
GMNN O75496 1/20 0.34
TP53 P04637 1/20 0.34
HSP90AA1 P07900 1/20 0.34
MMP2 P08253 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MMP9 P14780 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
MMP8 P22894 1/20 0.34
CCR1 P32246 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16381563 0.90 RXRA (0.36) MAPTKDM4ELMNAHTTSMN1; SMN2
SCHEMBL12011964 0.83 SLC40A1 (0.45) MAPTKDM4ELMNAHTTSMN1; SMN2
SCHEMBL8994539 0.82 PHGDH (0.34) KDM4ELMNASMN1; SMN2TSHRCCR1
SCHEMBL10311139 0.82 KDM4E (0.39) MAPTKDM4ELMNAHTTSMN1; SMN2
SCHEMBL15034016 0.81 ALDH1A1 (0.48) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL10044970 0.80 LMNA (0.42) MAPTKDM4ELMNAHTTSMN1; SMN2
SCHEMBL10045025 0.80 SLC40A1 (0.38) MAPTKDM4ELMNAHTTSMN1; SMN2
SCHEMBL10311138 0.77 ALDH1A1 (0.45) MAPTKDM4ELMNAHTTSMN1; SMN2
SCHEMBL12255209 0.74 VDR (0.33)
SCHEMBL764340 0.73 KAT2B (0.38) MMP2CYP3A4MMP13KAT2BRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355284-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-16 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-9368803-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-14 US disclosed
US-9368803-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-14 US disclosed
US-9178218-B2 Hyper-branched polymer, electrode and electrolyte membrane including the hyper-branched polymer, and fuel cell including at least one of the electrode and the electrolyte membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US disclosed
US-9178218-B2 Hyper-branched polymer, electrode and electrolyte membrane including the hyper-branched polymer, and fuel cell including at least one of the electrode and the electrolyte membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US disclosed
US-9096725-B2 Cross-linked polyazole, method of preparing the polyazole, electrode for fuel cell including the cross-linked polyazole, electrolyte membrane for fuel cell including the cross-linked polyazole, method of manufacturing the electrolyte membrane, and fuel cell including the cross-linked polyazole SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-08-04 US disclosed
US-9096725-B2 Cross-linked polyazole, method of preparing the polyazole, electrode for fuel cell including the cross-linked polyazole, electrolyte membrane for fuel cell including the cross-linked polyazole, method of manufacturing the electrolyte membrane, and fuel cell including the cross-linked polyazole SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-08-04 US disclosed
US-9006300-B2 Method for mechanically stabilizing nitrogen-containing polymers SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-04-14 US disclosed
US-20110195338-A1 HYPER-BRANCHED POLYMER, ELECTRODE AND ELECTROLYTE MEMBRANE INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-11 US disclosed
US-20110195338-A1 HYPER-BRANCHED POLYMER, ELECTRODE AND ELECTROLYTE MEMBRANE INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-11 US disclosed
US-20100273087-A1 CROSS-LINKED POLYAZOLE, METHOD OF PREPARING THE POLYAZOLE, ELECTRODE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, METHOD OF MANUFACTURING THE ELECTROLYTE MEMBRANE, AND FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-10-28 US disclosed
US-20100273087-A1 CROSS-LINKED POLYAZOLE, METHOD OF PREPARING THE POLYAZOLE, ELECTRODE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, METHOD OF MANUFACTURING THE ELECTROLYTE MEMBRANE, AND FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-10-28 US disclosed
EP-2221303-A1 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-08-25 EP disclosed
US-20100159347-A1 HYPER-BRANCHED POLYMER, ELECTRODE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-24 US disclosed
US-20100159347-A1 HYPER-BRANCHED POLYMER, ELECTRODE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-24 US disclosed
EP-2062891-A1 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode Samsung Electronics Co., Ltd. (KR) 2009-05-27 EP disclosed
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-05-07 US disclosed
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE HCN1, PXMP4, GJA1 GLO1 1807/4885MAPT 4048/4885KDM4E 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.