SCHEMBL476126

SCHEMBL476126

CC(=O)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.40
TSHR P16473 2/20 0.39
NAPRT Q6XQN6 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ESR1 P03372 2/20 0.39
HPGD P15428 2/20 0.39
ELANE P08246 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
HMGB1 P09429 1/20 0.39
GGT1 P19440 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704476 0.98 CES2 (0.41) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL132933 0.82 CES2 (0.43) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL132756 0.82 CES2 (0.43) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL28422623 0.81 LMNA (0.37) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL2184872 0.81 ELANE (0.46) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL150540 0.80 MAPT (0.43) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL475824 0.80 LMNA (0.48) CES2CES1ALDH1A1MAPTHPGD
SCHEMBL475969 0.80 MAPT (0.43) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL704615 0.80 CES2 (0.41) CES2CES1ALDH1A1MAPTTSHR
SCHEMBL475923 0.80 MAPT (0.43) CES2CES1ALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 US claimed
CN-102051120-A Super-hydrophobic coating material, preparation method thereof and super-hydrophobic coating HENKEL AG & CO KGAA 2011-05-11 CN claimed
CN-101892115-A Release agent and application thereof HENKEL CHINA INVEST CO LTD 2010-11-24 CN claimed
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof GILLARD MICHEL 2010-09-30 US claimed
US-20070161722-A1 Silyl Esters, Their Use in Binder Systems and Paint Compositions and a Process for Production Thereof SIGMA COATINGS B.V. (NL) 2007-07-12 US claimed
EP-1620514-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SigmaKalon B.V. (NL) 2006-02-01 EP claimed
EP-1606329-A1 A PROCESS FOR THE PRODUCTION OF ACID GROUP CONTAINING POLYMER RESIN SigmaKalon B.V. (NL) 2005-12-21 EP claimed
EP-1606338-A1 A PROCESS FOR THE PROTECTION OF ACID GROUPS IN POLYMERS SigmaKalon B.V. (NL) 2005-12-21 EP claimed
US-20050222446-A1 Process for the production of hydrocarbyl silyl carboxylate compounds SIGMA COATINGS B.V. (NL) 2005-10-06 US claimed
EP-1572701-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2005-09-14 EP claimed
WO-2004099326-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SIGMAKALON B.V. (NL) 2004-11-18 WO claimed
EP-1475415-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SigmaKalon Services B.V. (NL) 2004-11-10 EP claimed
WO-2004085518-A1 A PROCESS FOR THE PROTECTION OF ACID GROUPS IN POLYMERS SIGMAKALON B.V. (NL) 2004-10-07 WO claimed
WO-2004085502-A1 A PROCESS FOR THE PRODUCTION OF ACID GROUP CONTAINING POLYMER RESIN SIGMAKALON B.V. (NL) 2004-10-07 WO claimed
EP-1462472-A1 A process for the protection of acid groups in polymers Sigma Kalon Services B.V. (NL) 2004-09-29 EP claimed
EP-1462467-A1 A process for the production of silyl group containing polymer resin Sigma Kalon Services B.V. (NL) 2004-09-29 EP claimed
WO-2004056837-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2004-07-08 WO claimed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof LCT, PCMT1, TST CES2 461/4885CES1 907/4885ALDH1A1 2426/4885
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 CES2 2753/4885CES1 2191/4885ALDH1A1 3642/4885
US-20050222446-A1 Process for the production of hydrocarbyl silyl carboxylate compounds FTO, SUCLG2, ALKBH3 CES2 200/4885CES1 349/4885ALDH1A1 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.