SCHEMBL150565

SCHEMBL150565

C=C(C)C(=O)OCCc1cccc(-c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.52
BCL2 P10415 1/20 0.42
FFAR1 O14842 1/20 0.42
AKR1B1 P15121 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
AOC3 Q16853 2/20 0.42
THRB P10828 1/20 0.41
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP12 P39900 2/20 0.41
APP P05067 1/20 0.41
NR4A2 P43354 1/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CHRM5 P08912 2/20 0.41
CHRM1 P11229 2/20 0.41
AGXT P21549 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29734670 1.00 MGLL (0.52) MGLLBCL2FFAR1AKR1B1FFAR4
SCHEMBL28186333 0.88 APP (0.46) MGLLAKR1B1THRBMMP1MMP2
SCHEMBL146127 0.87 FFAR1 (0.49) MGLLFFAR1THRBMMP2MMP12
SCHEMBL42893 0.86 HCAR2 (0.51) AKR1B1THRBMMP1MMP2MMP12
SCHEMBL10890254 0.85 MMP1 (0.52) MGLLBCL2FFAR1AKR1B1FFAR4
Methane SCHEMBL4468486 0.85 HCAR2 (0.50) AKR1B1THRBMMP1MMP2MMP12
SCHEMBL12925504 0.83 MGLL (0.40) MGLLBCL2AKR1B1THRBAPP
SCHEMBL31567618 0.83 FDFT1 (0.47) FFAR1FFAR4TDP1
Methacrylic Acid SCHEMBL8131805 0.83 HCAR2 (0.49) AKR1B1THRBMMP1MMP2MMP12
SCHEMBL27973892 0.83 HCAR2 (0.49) FFAR1AKR1B1THRBMMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
US-20240142665-A1 OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2024-05-02 US claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
US-20240117092-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2024-04-11 US claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
EP-4284787-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-12-06 EP claimed
WO-2023218463-A1 RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-16 WO claimed
EP-1177227-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2002-02-06 EP claimed
US-20020007032-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2002-01-17 US claimed
US-20010056165-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2001-12-27 US claimed
US-6281319-B1 HYDRATABLE POLYMER SURGIDEV CORPORATION 2001-08-28 US claimed
EP-1080382-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS Alcon Laboratories, Inc. (US) 2001-03-07 EP claimed
WO-2000061646-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2000-10-19 WO claimed
US-6001128-A CROSSLINKED ACRYLATED ESTER ALCON LABORATORIES, INC. (US) 1999-12-14 US claimed
WO-1999053347-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS ALCON LABORATORIES, INC. (US) 1999-10-21 WO claimed
EP-0914169-A2 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LABORATORIES, INC. (US) 1999-05-12 EP claimed
WO-1998053862-A2 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LABORATORIES, INC. (US) 1998-12-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA MGLL 3580/4885BCL2 582/4885FFAR1 375/4885
US-20240117092-A1 OPTICALLY ACTIVE DEVICES PDE6C, UACA, PDE6A MGLL 1856/4885BCL2 4793/4885FFAR1 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.