Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519312 | 0.87 | — | — | |
| SCHEMBL30891 | 0.80 | — | — | |
| SCHEMBL2631271 | 0.79 | ACHE (0.41) | ACHE | |
| SCHEMBL16426590 | 0.79 | — | — | |
| SCHEMBL4212327 | 0.77 | NAMPT (0.34) | — | |
| SCHEMBL18580542 | 0.77 | GSK3B (0.37) | — | |
| SCHEMBL2380057 | 0.77 | ACHE (0.35) | ACHE | |
| SCHEMBL455008 | 0.77 | KMT2A (0.30) | — | |
| SCHEMBL4208996 | 0.74 | L3MBTL1 (0.40) | — | |
| SCHEMBL875563 | 0.73 | ACHE (0.44) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955546-A | Synthesis method of compound 1-isopropyl pyrazole-3-boric acid pinacol ester | 上海毕得医药科技股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| US-12428394-B2 | 2,4-disubstituted pyrimidine derivative, preparation method therefor and use thereof | CHENGDU ZENITAR BIOMEDICAL TECHNOLOGY CO., LTD. (CN) | 2025-09-30 | — | — | US | disclosed |
| EP-3947366-B1 | HPK1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-05-21 | — | — | EP | disclosed |
| CN-118955546-A | Synthesis method of compound 1-isopropyl pyrazole-3-boric acid pinacol ester | 上海毕得医药科技股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118955546-A | Synthesis method of compound 1-isopropyl pyrazole-3-boric acid pinacol ester | 上海毕得医药科技股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-3985000-B1 | 2,4-DISUBSTITUTED PYRIMIDINE DERIVATIVE, PREPARATION METHOD FOR SAME, AND USES THEREOF | CHENGDU ZENITAR BIOMEDICAL TECH CO LTD (CN) | 2024-09-25 | — | — | EP | disclosed |
| CN-114423750-B | 2, 4-Disubstituted pyrimidine derivative, preparation method and application thereof | 成都赜灵生物医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023169453-A1 | HETEROAROMATIC RING-CONTAINING ALKYNYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-09-14 | — | — | WO | disclosed |
| CN-116730978-A | Compound containing heteroaromatic ring alkynyl, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-09-12 | — | — | CN | disclosed |
| US-20220298140-A1 | 2,4-DISUBSTITUTED PYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CHENGDU ZENITAR BIOMEDICAL TECHNOLOGY CO., LTD. (CN) | 2022-09-22 | — | — | US | disclosed |
| US-20170174624-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | ABBVIE INC. (US) | 2017-06-22 | — | — | US | disclosed |
| US-20170073333-A1 | New Pyrazolyl-substituted Heteroaryls and their use as Medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-16 | — | — | US | disclosed |
| US-9567339-B2 | Primary carboxamides as BTK inhibitors | ABBVIE INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9399645-B2 | Inhibitors of HIV replication | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-07-26 | — | — | US | disclosed |
| US-20150011531-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-08 | — | — | US | disclosed |
| US-8927536-B2 | Tetrahydrothiazepine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-01-06 | — | — | US | disclosed |
| US-20150005279-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | ABBVIE INC. (US) | 2015-01-01 | — | — | US | disclosed |
| EP-2794613-A1 | CONDENSED TRICLYCLIC COMPOUNDS AS INHIBITORS OF HIV REPLICATION | Boehringer Ingelheim International GmbH (DE) | 2014-10-29 | — | — | EP | disclosed |
| US-20140080808-A1 | TETRAHYDROTHIAZEPINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-03-20 | — | — | US | disclosed |
| WO-2013091096-A1 | CONDENSED TRICLYCLIC COMPOUNDS AS INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005279-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | BTK, SYK, MYD88 | ACHE 4225/4885LRRK2 2155/4885 |
| US-20220298140-A1 | 2,4-DISUBSTITUTED PYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | JAK2, FLT3, JAK1 | ACHE 4847/4885LRRK2 1741/4885 |
| US-20170073333-A1 | New Pyrazolyl-substituted Heteroaryls and their use as Medicaments | HRH4, HRH2, HRH3 | ACHE 3050/4885LRRK2 619/4885 |
| US-12428394-B2 | 2,4-disubstituted pyrimidine derivative, preparation method therefor and use thereof | JAK2, FLT3, JAK1 | ACHE 4847/4885LRRK2 1741/4885 |
| US-20140080808-A1 | TETRAHYDROTHIAZEPINE DERIVATIVE | HSD11B1, HSD11B2, HSD3B1 | ACHE 1758/4885LRRK2 1799/4885 |
| US-20150011531-A1 | INHIBITORS OF HIV REPLICATION | MCM3, REV1, POLR2E | ACHE 2208/4885LRRK2 1309/4885 |
| US-20170174624-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | BTK, SYK, MYD88 | ACHE 4225/4885LRRK2 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.