Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017170 | 0.85 | ALOX5AP (0.48) | ALOX5APFEN1RORCGPR84SCN9A | |
| SCHEMBL266175 | 0.80 | RORC (0.54) | ALOX5APFEN1RORCGPR84SCN9A | |
| SCHEMBL15060604 | 0.72 | CYP1A2 (0.45) | ALOX5APFEN1HSD11B1ABL1CNR2 | |
| SCHEMBL14744175 | 0.72 | ALOX5AP (0.51) | ALOX5APFEN1RORCGPR84SCN9A | |
| SCHEMBL13017150 | 0.71 | RORC (0.49) | ALOX5APFEN1RORCGPR84SCN9A | |
| SCHEMBL8230055 | 0.70 | GRM5 (0.52) | ALOX5APFEN1GPR84SCN9AHSD11B1 | |
| SCHEMBL27955785 | 0.70 | HSD11B1 (0.50) | ALOX5APFEN1SCN9AHSD11B1TRPA1 | |
| SCHEMBL7701143 | 0.70 | ALDH1A1 (0.50) | ALOX5APFEN1SCN9AHSD11B1FFAR4 | |
| SCHEMBL14744389 | 0.69 | RORC (0.45) | ALOX5APFEN1RORCSCN9AMETAP2 | |
| SCHEMBL2553137 | 0.69 | ABL1 (0.44) | ALOX5APFEN1RORCSCN9AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471024-B2 | Tetrahydrofuropyridones | MERCK SHARP & DOHME, CORP. (US) | 2013-06-25 | — | — | US | disclosed |