SCHEMBL29402769

SCHEMBL29402769

COC1=C(OC)C(=O)C(C/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C)=C(C)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
MAOB P27338 2/20 0.68
PTGS1 P23219 3/20 0.66
PGR P06401 1/20 0.66
HTR1A P08908 1/20 0.66
ADORA3 P0DMS8 1/20 0.66
MAPT P10636 1/20 0.66
PDE4A P27815 1/20 0.66
MAPK1 P28482 1/20 0.66
DRD3 P35462 1/20 0.66
SNCA P37840 1/20 0.66
PDE3A Q14432 1/20 0.66
ALOX5 P09917 9/20 0.62
ALOX15 P16050 1/20 0.47
APP P05067 4/20 0.46
BACE1 P56817 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9975753 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL29358434 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Coenzyme Q4 SCHEMBL6279408 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL13026488 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL11901691 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL19858 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL16393869 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL5530210 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Coenzyme Q4 SCHEMBL6279406 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Coenzyme Q6 SCHEMBL29404151 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041336-A1 PLATELET REACTIVITY EXPRESSION SCORE PREDICTS CARDIOVASCULAR RISK NEW YORK UNIVERSITY (US) 2026-02-12 US claimed
WO-2025231487-A1 PHOTORECEPTOR SPECIFIC PROMOTORS FOR USE IN GENE THERAPIES FOR TREATMENT OF RETINAL DEGENERATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-11-06 WO claimed
US-20250262169-A1 METHODS OF TREATING COENZYME Q10 DEFICIENCY THLIVERIS, ANDREW T. 2025-08-21 US claimed
CN-118531016-B Nucleic acid molecule, expression cassette, recombinant strain and application thereof 新开利安生物科技(海南)有限公司 2025-04-04 CN claimed
CN-119120695-A Genetic marker, metabolic marker and kit for statin muscle toxicity 中日友好医院(中日友好临床医学研究所) 2024-12-13 CN claimed
CN-117587128-B Biomarker combinations and their use in predicting and/or diagnosing colorectal cancer 上海爱谱蒂康生物科技有限公司 2024-10-22 CN claimed
CN-118531016-A Nucleic acid molecule, expression cassette, recombinant strain and application thereof 新开利安生物科技(海南)有限公司 2024-08-23 CN claimed
US-12024750-B2 Methylation markers and targeted methylation probe panel GRAIL, LLC (US) 2024-07-02 US claimed
CN-117587128-A Biomarker combinations and their use in predicting and/or diagnosing colorectal cancer 上海爱谱蒂康生物科技有限公司 2024-02-23 CN claimed
WO-2024039764-A2 EPITRANSCRIPTOMIC ANALYSIS OF GLIOMA OHIO STATE INNOVATION FOUNDATION (US) 2024-02-22 WO claimed
US-20230282308-A1 Systems-level Analysis of 32 TCGA Cancers Reveals Disease-Dependent tRNA Fragmentation Patterns and Very Selective Associations with Messenger RNAs and Repeat Elements THOMAS JEFFERSON UNIVERSITY (US) 2023-09-07 US claimed
US-20230193205-A1 GENE MODIFIED FIBROBLASTS FOR THERAPEUTIC APPLICATIONS FIGENE, LLC 2023-06-22 US claimed
US-20230093080-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-03-23 US claimed
US-20220409554-A1 ASCORBIC ACID AND QUINONE COMPOUND FOR CANCER TREATMENT IC-MedTech Corp. 2022-12-29 US claimed
US-11485743-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2022-11-01 US claimed
US-20220243273-A1 BLOOD RNA BIOMARKERS OF CORONARY ARTERY DISEASE THE GEORGE WASHINGTON UNIVERSITY 2022-08-04 US claimed
US-12636369-B2 Compositions comprising circular polyribonucleotides for protein modulation and uses thereof FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2026-05-26 US disclosed
CN-121950947-A Method for improving content of Antrodia camphorate triterpene compounds by using recombinant yeast methyltransferase 江西根稷企业管理服务有限公司 2026-05-01 CN disclosed
US-11285125-B2 Oxidative retinal diseases RETROTOPE, INC. (US) 2022-03-29 US disclosed
US-11274281-B2 Exosomes from clonal progenitor cells ReCyte Therapeutics, Inc. (US) 2022-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485743-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 LMNA 2563/4885MAOB 2702/4885PTGS1 4442/4885
US-20230093080-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 LMNA 2563/4885MAOB 2702/4885PTGS1 4442/4885
US-11285125-B2 Oxidative retinal diseases ALDH1A2, TXNRD2, STARD3 LMNA 1713/4885MAOB 2923/4885PTGS1 205/4885
US-20250262169-A1 METHODS OF TREATING COENZYME Q10 DEFICIENCY NDUFB10, NDUFA10, NDUFB11 LMNA 1283/4885MAOB 664/4885PTGS1 1676/4885
US-20260041336-A1 PLATELET REACTIVITY EXPRESSION SCORE PREDICTS CARDIOVASCULAR RISK EPB41L2, MYLK2, RABL3 LMNA 4313/4885MAOB 4087/4885PTGS1 3091/4885
US-12636369-B2 Compositions comprising circular polyribonucleotides for protein modulation and uses thereof USP25, RBM25, TRIM25 LMNA 1111/4885MAOB 4226/4885PTGS1 4262/4885
US-20220409554-A1 ASCORBIC ACID AND QUINONE COMPOUND FOR CANCER TREATMENT NQO1, SDHB, SDHA LMNA 2639/4885MAOB 372/4885PTGS1 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.