Coenzyme Q4

Coenzyme Q4

SCHEMBL6279406

COC1=C(OC)C(=O)C(C/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C)=C(C)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 1.00
▸ MAOB P27338 2/20 0.68
▸ PTGS1 P23219 3/20 0.66
▸ PGR P06401 1/20 0.66
▸ HTR1A P08908 1/20 0.66
▸ ADORA3 P0DMS8 1/20 0.66
▸ MAPT P10636 1/20 0.66
▸ PDE4A P27815 1/20 0.66
▸ MAPK1 P28482 1/20 0.66
▸ DRD3 P35462 1/20 0.66
▸ SNCA P37840 1/20 0.66
▸ PDE3A Q14432 1/20 0.66
▸ ALOX5 P09917 9/20 0.62
▸ ALOX15 P16050 1/20 0.47
▸ APP P05067 4/20 0.46
▸ BACE1 P56817 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402769 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL5530210 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL29358434 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL11901691 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL19858 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL16393869 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Coenzyme Q4 SCHEMBL6279408 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
SCHEMBL9975753 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Ubidecarenone SCHEMBL13026488 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A
Coenzyme Q6 SCHEMBL29404151 1.00 LMNA (1.00) LMNAMAOBPTGS1PGRHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120060462-B Neonate genetic disease screening gene combination, probe combination, kit, preparation method and device thereof 东莞博奥木华基因科技有限公司 2026-05-19 — — CN claimed
WO-2025231487-A1 PHOTORECEPTOR SPECIFIC PROMOTORS FOR USE IN GENE THERAPIES FOR TREATMENT OF RETINAL DEGENERATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-11-06 — — WO claimed
US-20250262169-A1 METHODS OF TREATING COENZYME Q10 DEFICIENCY THLIVERIS, ANDREW T. 2025-08-21 — — US claimed
WO-2025059302-A1 COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT AND MODULATION OF ACUTE AND CHRONIC SYMPTOMS OF MITOCHONDRIAL DISEASE AND DYSFUNCTION THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2025-03-20 — — WO claimed
CN-110869494-B Without systemic immunosuppression allograft tolerance 西奈卫生系统公司 2025-02-18 — — CN claimed
WO-2025035032-A2 METHODS AND COMPOSITIONS FOR PROVIDING CUSTOMIZED NUTRITIONAL SUPPLEMENTS VIBRANT HOLDINGS, LLC (US) 2025-02-13 — — WO claimed
US-20250000817-A1 Methods of Treating Mitochondrial Dysfunction RIBONOVA INC. (US) 2025-01-02 — — US claimed
EP-3334484-B1 COMPOSITIONS THAT PROMOTE HYPOXIA OR THE HYPOXIA RESPONSE FOR THE TREATMENT AND PREVENTION OF MITOCHONDRIAL DYSFUNCTION MASSACHUSETTS GEN HOSPITAL (US) 2024-12-25 — — EP claimed
EP-4397369-A2 METHODS OF TREATING MITOCHONDRIAL DYSFUNCTION Ribonova Inc. (US) 2024-07-10 — — EP claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN claimed
US-20230193205-A1 GENE MODIFIED FIBROBLASTS FOR THERAPEUTIC APPLICATIONS FIGENE, LLC 2023-06-22 — — US claimed
US-20230146253-A1 METHODS RELATED TO BRONCHIAL PREMALIGNANT LESION SEVERITY AND PROGRESSION TRUSTEES OF BOSTON UNIVERSITY (US) 2023-05-11 — — US claimed
EP-4162277-A1 CELLULAR RESPONSE ASSAYS FOR LUNG CANCER Precyte Inc. (US) 2023-04-12 — — EP claimed
US-20230093080-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-03-23 — — US claimed
US-11579140-B2 Methods related to bronchial premalignant lesion severity and progression TRUSTEES OF BOSTON UNIVERSITY (US) 2023-02-14 — — US claimed
US-20220409554-A1 ASCORBIC ACID AND QUINONE COMPOUND FOR CANCER TREATMENT IC-MedTech Corp. 2022-12-29 — — US claimed
US-11485743-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2022-11-01 — — US claimed
US-12630821-B2 Selective curbing of unwanted RNA editing (SECURE) DNA base editor variants THE GENERAL HOSPITAL CORPORATION (US) 2026-05-19 — — US disclosed
US-20220073919-A1 THERAPEUTIC OLIGONUCLEOTIDES WILMINGTON TRUST, NATIONAL ASSOCIATION 2022-03-10 — — US disclosed
JP-2005232181-A ANTI-OSTEOPOROSIS DRUG EISAI CO LTD 2005-09-02 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485743-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 LMNA 2563/4885MAOB 2702/4885PTGS1 4442/4885
US-20230093080-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 LMNA 2563/4885MAOB 2702/4885PTGS1 4442/4885
US-20250000817-A1 Methods of Treating Mitochondrial Dysfunction SLC25A20, NDUFAB1, HAGH LMNA 411/4885MAOB 1111/4885PTGS1 1528/4885
US-20250262169-A1 METHODS OF TREATING COENZYME Q10 DEFICIENCY NDUFB10, NDUFA10, NDUFB11 LMNA 1283/4885MAOB 664/4885PTGS1 1676/4885
US-12630821-B2 Selective curbing of unwanted RNA editing (SECURE) DNA base editor variants AMPD1, AMPD2, AMPD3 LMNA 217/4885MAOB 688/4885PTGS1 4707/4885
US-20220409554-A1 ASCORBIC ACID AND QUINONE COMPOUND FOR CANCER TREATMENT NQO1, SDHB, SDHA LMNA 2639/4885MAOB 372/4885PTGS1 695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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