SCHEMBL1506807

SCHEMBL1506807

CC(C)(C)COB(O)c1ccccc1CBr

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.33
ENPP2 Q13822 1/20 0.31
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852415 0.86 LIPG (0.31) LIPG
SCHEMBL1930883 0.77 LIPG (0.36) LIPGENPP2ORAI1ORAI2ORAI3
SCHEMBL580069 0.76 LIPG (0.33) LIPGENPP2
SCHEMBL29663650 0.74 LIPG (0.53) LIPGENPP2ORAI1ORAI2ORAI3
SCHEMBL580318 0.74 LIPG (0.53) LIPGENPP2ORAI1ORAI2ORAI3
SCHEMBL6940800 0.70 LPL (0.33) LIPG
SCHEMBL31416560 0.70 ALOX5 (0.33)
Bromoethanamine SCHEMBL14119092 0.67 LIPG (0.46) LIPGENPP2ORAI1ORAI2ORAI3
SCHEMBL2228334 0.67 RIPK1 (0.44)
SCHEMBL31416562 0.65 RIPK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292626-B1 Detection of analytes in aqueous environments SENSEONICS INC (US) 2014-05-21 EP disclosed
EP-1557422-B1 Detection of analytes in aqueous environments SENSEONICS INC (US) 2013-12-25 EP disclosed
EP-1307464-B1 DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS SENSEONICS INC (US) 2013-02-13 EP disclosed
US-7939332-B2 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2011-05-10 US disclosed
EP-2292626-A1 Detection of analytes in aqueous environments Sensors for Medicine and Science, Inc. (US) 2011-03-09 EP disclosed
EP-1490359-B1 DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE SENSORS FOR MED & SCIENCE INC (US) 2010-05-19 EP disclosed
US-20060281185-A1 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2006-12-14 US disclosed
EP-1490359-A4 DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE SENSORS FOR MED & SCIENCE INC (US) 2006-08-23 EP disclosed
US-7078554-B2 Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2006-07-18 US disclosed
US-7060503-B2 Detection of Analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2006-06-13 US disclosed
EP-1307464-A1 DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS Sensors for Medicine and Science, Inc. (US) 2003-05-07 EP disclosed
US-20030082663-A1 Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone SENSORS FOR MEDICINE AND SCIENCE, INC. 2003-05-01 US disclosed
US-20020127626-A1 Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-09-12 US disclosed
US-20020119581-A1 Detection of analytes SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-08-29 US disclosed
WO-2002057788-A2 DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2002-07-25 WO disclosed
US-20020094586-A1 Detection of analytes SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2002-07-18 US disclosed
WO-2002054067-A2 DETECTION OF ANALYTES SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2002-07-11 WO disclosed
US-20020090734-A1 Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-07-11 US disclosed
US-20020039793-A1 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-04-04 US disclosed
WO-2002012251-A1 DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2002-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060281185-A1 Detection of analytes in aqueous environments MPI, NEFM, CD44 LIPG 2797/4885ENPP2 2977/4885ORAI1 1748/4885
US-20020094586-A1 Detection of analytes AKR7A2, DDX6, ANXA6 LIPG 2427/4885ENPP2 1551/4885ORAI1 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.