SCHEMBL1506809

SCHEMBL1506809

C=C(C)C(=O)NCCCNS(=O)(=O)c1cc2c(c(O)c1O)C(=O)c1ccccc1C2=O

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKLR P30613 12/20 0.67
PGAM1 P18669 9/20 0.48
PTPN1 P18031 2/20 0.47
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12658885 0.69 MAPT (0.55) ALDH1A1LMNATHRBL3MBTL1
SCHEMBL12304032 0.69 PGAM1 (0.73) PKLRPGAM1PTPN1
SCHEMBL13039223 0.67 TDP1 (0.34) ALDH1A1
SCHEMBL13039208 0.67 BRD4 (0.33) PKLRALDH1A1
SCHEMBL13041270 0.67 BRD4 (0.33) PKLRALDH1A1
SCHEMBL1071678 0.67 MEN1 (0.57) ALDH1A1LMNAL3MBTL1
SCHEMBL28768751 0.67 MAOA (0.55) ALDH1A1LMNAL3MBTL1
Alizarin Red SCHEMBL29372853 0.67 PGAM1 (1.00) PKLRPGAM1PTPN1ALDH1A1
Alizarin Red SCHEMBL1203855 0.67 PGAM1 (1.00) PKLRPGAM1PTPN1ALDH1A1
Alizarin Red SCHEMBL29630358 0.67 PGAM1 (1.00) PKLRPGAM1PTPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292626-B1 Detection of analytes in aqueous environments SENSEONICS INC (US) 2014-05-21 EP claimed
EP-1557422-B1 Detection of analytes in aqueous environments SENSEONICS INC (US) 2013-12-25 EP claimed
EP-1307464-B1 DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS SENSEONICS INC (US) 2013-02-13 EP claimed
US-7939332-B2 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2011-05-10 US claimed
EP-2292626-A1 Detection of analytes in aqueous environments Sensors for Medicine and Science, Inc. (US) 2011-03-09 EP claimed
WO-2007011691-A2 IMPLANTABLE DEVICE FOR DETECTING AN ANALYTE IN VIVO SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2007-01-25 WO claimed
US-20070014726-A1 Oxidation-resistant indicator macromolecule SENSORS FOR MEDICINE AND SCIENCE (US) 2007-01-18 US claimed
US-20060281185-A1 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2006-12-14 US claimed
US-7060503-B2 Detection of Analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2006-06-13 US claimed
EP-1557422-A2 Detection of analytes in aqueous environments Sensors for Medicine and Science, Inc. (US) 2005-07-27 EP claimed
US-20040229370-A1 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2004-11-18 US claimed
US-6794195-B2 QUANTITATIVE, QUALITATIVE ANALYSIS SENSORS FOR MEDICINE & SCIENCE, INC. 2004-09-21 US claimed
EP-1307464-A1 DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS Sensors for Medicine and Science, Inc. (US) 2003-05-07 EP claimed
US-20020039793-A1 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-04-04 US claimed
WO-2002012251-A1 DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2002-02-14 WO claimed
EP-2292626-B1 Detection of analytes in aqueous environments SENSEONICS INC (US) 2014-05-21 EP disclosed
EP-1557422-B1 Detection of analytes in aqueous environments SENSEONICS INC (US) 2013-12-25 EP disclosed
US-20020090734-A1 Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-07-11 US disclosed
US-20020039793-A1 Detection of analytes in aqueous environments SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-04-04 US disclosed
WO-2002012251-A1 DETECTION OF ANALYTES IN AQUEOUS ENVIRONMENTS SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2002-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070014726-A1 Oxidation-resistant indicator macromolecule MB, LPO, GPX4 PKLR 3112/4885PGAM1 867/4885PTPN1 3819/4885
US-20060281185-A1 Detection of analytes in aqueous environments MPI, NEFM, CD44 PKLR 2757/4885PGAM1 498/4885PTPN1 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.