Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 1.00 |
| ▸ | CDC25B | P30305 | 4/20 | 1.00 |
| ▸ | TDP2 | O95551 | 3/20 | 0.58 |
| ▸ | NSD2 | O96028 | 3/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.53 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.53 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.53 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29747118 | 1.00 | S100A4 (1.00) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL12231792 | 0.84 | S100A4 (0.71) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL22013897 | 0.77 | CDC25B (0.63) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL30646118 | 0.77 | CDC25B (0.63) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL6212776 | 0.77 | S100A4 (0.63) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL31747733 | 0.77 | S100A4 (0.63) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL28803385 | 0.77 | S100A4 (0.61) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL5915065 | 0.73 | TDP2 (0.81) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL460433 | 0.73 | TDP2 (1.00) | S100A4CDC25BTDP2NSD2PAX8 | |
| Phanquone SCHEMBL7633567 | 0.73 | MEN1 (1.00) | S100A4CDC25BTDP2NSD2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4427812-A2 | SUBSTITUTED BICYCLIC AND TETRACYCLIC QUINONES AND RELATED METHODS OF USE | The Regents of the University of Michigan (US) | 2024-09-11 | — | — | EP | claimed |
| EP-3934634-B1 | SUBSTITUTED BICYCLIC AND TETRACYCLIC QUINONES AND RELATED METHODS OF USE | UNIV MICHIGAN REGENTS (US) | 2024-07-24 | — | — | EP | claimed |
| CN-108299415-B | Quinolinequinone derivative and preparation method and application thereof | 南通大学 | 2020-11-10 | — | — | CN | claimed |
| WO-2020055192-A2 | PREPARATION METHOD FOR QUINOLINE-5, 8-DIONE DERIVATIVE WHICH IS TGASE 2 INHIBITOR | 재단법인 대구경북첨단의료산업진흥재단 | 2020-03-19 | — | — | WO | claimed |
| EP-2257515-B1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2017-05-17 | — | — | EP | claimed |
| US-9096519-B2 | Process for the synthesis of ketones from internal alkenes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-08-04 | — | — | US | claimed |
| US-20140194604-A1 | PROCESS FOR THE SYNTHESIS OF KETONES FROM INTERNAL ALKENES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-07-10 | — | — | US | claimed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | claimed |
| CN-101712648-B | Synthesis method of azepine anthraquinone | NANJING UNIVERSITY OF TECHNOLOGY | 2011-11-09 | — | — | CN | claimed |
| US-20110059972-A1 | 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-10 | — | — | US | claimed |
| EP-2257515-A1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF | Centre National de la Recherche Scientifique (FR) | 2010-12-08 | — | — | EP | claimed |
| CN-101712648-A | Synthesis method of azepine anthraquinone | NANJING UNIVERSITY OF TECHNOLOGY | 2010-05-26 | — | — | CN | claimed |
| WO-2009118327-A1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-10-01 | — | — | WO | claimed |
| JP-2003507363-A | — | — | 2003-02-25 | — | — | JP | claimed |
| US-6515127-B1 | The invention concerns a method for preparing quinoline-5,8-diones of formula (I) light-induced oxygenation of a 8-hydroxyquinoline. and intermediates | LABORATOIRE L. LAFON (FR) | 2003-02-04 | — | — | US | claimed |
| EP-1202972-A2 | METHOD FOR PREPARING QUINOLINE-5,8-DIONES | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | claimed |
| WO-2001012597-A2 | METHOD FOR PREPARING QUINOLINE-5,8-DIONES | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | claimed |
| EP-0519290-A1 | Use of 6(7)-amino-substituted-5,8-quinolinediones to combat endoparasites, new 6(7)-aminosubstituted 5,8-quinolinediones and processes for their preparation | BAYER AG (DE) | 1992-12-23 | — | — | EP | claimed |
| EP-0251094-A2 | Substituted quinoxalinediones and quinolinediones | AMERICAN CYANAMID COMPANY (US) | 1988-01-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | S100A4, S100A6, S100A10 | S100A4 1/4885CDC25B 211/4885TDP2 4122/4885 |
| US-20140194604-A1 | PROCESS FOR THE SYNTHESIS OF KETONES FROM INTERNAL ALKENES | FASN, NOTUM, DGAT2 | S100A4 2853/4885CDC25B 2960/4885TDP2 3886/4885 |
| US-20110059972-A1 | 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF | NQO1, NDUFV2, RECQL | S100A4 3370/4885CDC25B 576/4885TDP2 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.