SCHEMBL15081180

SCHEMBL15081180

CC(C)[C@]1(C(=O)O)C[C@@H](O)[C@@H](C)[C@H]([C@H](O)[C@H](O)CO)O1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ NEU1 Q99519 9/20 0.36
▸ NEU4 Q8WWR8 6/20 0.36
▸ NEU2 Q9Y3R4 8/20 0.34
▸ NEU3 Q9UQ49 6/20 0.34
▸ NANP Q8TBE9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23640230 0.88 L3MBTL1 (0.50) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL23591471 0.88 L3MBTL1 (0.50) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL19960936 0.86 L3MBTL1 (0.48) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL23640384 0.82 NANP (0.53) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL25518923 0.82 NANP (0.53) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL20122292 0.82 NANP (0.53) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL15143174 0.81 L3MBTL1 (0.72) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL15148465 0.81 L3MBTL1 (0.72) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL22199276 0.81 L3MBTL1 (0.51) L3MBTL1NEU1NEU4NEU2NEU3
SCHEMBL10077898 0.81 L3MBTL1 (0.72) L3MBTL1NEU1NEU4NEU2NEU3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005807-B2 Synthesis of sialylated/fucosylated human milk oligosaccharides GLYCOM A/S (DK) 2018-06-26 — — US disclosed
US-9963729-B2 Diversification of human milk oligosaccharides (HMOs) or precursors thereof GLYCOM A/S (DK) 2018-05-08 — — US disclosed
US-20160289721-A1 DIVERSIFICATION OF HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF GLYCOM A/S (DK) 2016-10-06 — — US disclosed
US-9382564-B2 Diversification of human milk oligosaccharides (HMOs) or precursors thereof GLYCOM A/S (DK) 2016-07-05 — — US disclosed
US-20160113952-A1 Synthetic Mixture of Oligosaccharides for Treating a Microbiota of a Mammal GLYCOM A/S (DK) 2016-04-28 — — US disclosed
US-20160075729-A1 SYNTHESIS OF SIALYLATED/FUCOSYLATED HUMAN MILK OLIGOSACCHARIDES GLYCOM A/S (DK) 2016-03-17 — — US disclosed
US-20160024129-A1 SYNTHESIS OF NEW SIALOOLIGOSACCHARIDE DERIVATIVES GLYCOM A/S (DK) 2016-01-28 — — US disclosed
US-9234225-B2 Method for generating human milk oligosaccharides (HMOs) or precursors thereof GLYCOM A/S (DK) 2016-01-12 — — US disclosed
US-9102966-B2 Synthesis of sialooligosaccharide derivatives GLYCOM A/S (DK) 2015-08-11 — — US disclosed
US-20150182549-A1 METHOD FOR ENZYMATIC GLYCOSYLATION OF OLIGOSACCHARIDES FROM MAMMALIAN ANIMAL MILK GLYCOM A/S (DK) 2015-07-02 — — US disclosed
US-20140248415-A1 NUTRITIONAL PRODUCTS COMPRISING HUMAN MILK OLIGOSACCHARIDES AND METHODS FOR MANUFACTURE THEREOF NESTEC S.A. (CH) 2014-09-04 — — US disclosed
US-20140234912-A1 METHOD FOR GENERATING HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF GLYCOM A/S (DK) 2014-08-21 — — US disclosed
US-20140212930-A1 DIVERSIFICATION OF HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF GLYCOM A/S (DK) 2014-07-31 — — US disclosed
US-20140057868-A1 CATALYTIC HYDROGENOLYSIS OF A COMPOSITION OF A MIXTURE OF OLIGOSACCHARIDE PRECURSORS AND USES THEREOF GLYCOM A/S (DK) 2014-02-27 — — US disclosed
US-20130172548-A1 DERIVATIZATION OF OLIGOSACCHARIDES Glycom A/S, Kgs. (DK) 2013-07-04 — — US disclosed
US-20130171696-A1 SYNTHESIS OF NEW SIALOOLIGOSACCHARIDE DERIVATIVES GLYCOM A/S (DK) 2013-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172548-A1 DERIVATIZATION OF OLIGOSACCHARIDES OSTC, OGA, FUT5 L3MBTL1 3544/4885NEU1 68/4885NEU4 20/4885
US-20140057868-A1 CATALYTIC HYDROGENOLYSIS OF A COMPOSITION OF A MIXTURE OF OLIGOSACCHARIDE PRECURSORS AND USES THEREOF MGAM, SI, GALK1 L3MBTL1 3111/4885NEU1 81/4885NEU4 125/4885
US-20160075729-A1 SYNTHESIS OF SIALYLATED/FUCOSYLATED HUMAN MILK OLIGOSACCHARIDES FUT6, ST6GAL1, FUCA1 L3MBTL1 708/4885NEU1 20/4885NEU4 39/4885
US-10005807-B2 Synthesis of sialylated/fucosylated human milk oligosaccharides FUT6, ST6GAL1, ST3GAL3 L3MBTL1 1328/4885NEU1 15/4885NEU4 28/4885
US-20160113952-A1 Synthetic Mixture of Oligosaccharides for Treating a Microbiota of a Mammal FUT5, FUT6, FUCA1 L3MBTL1 646/4885NEU1 27/4885NEU4 34/4885
US-20150182549-A1 METHOD FOR ENZYMATIC GLYCOSYLATION OF OLIGOSACCHARIDES FROM MAMMALIAN ANIMAL MILK GALE, SI, FUT6 L3MBTL1 1631/4885NEU1 22/4885NEU4 20/4885
US-20160024129-A1 SYNTHESIS OF NEW SIALOOLIGOSACCHARIDE DERIVATIVES FUCA1, FUT5, FUCA2 L3MBTL1 2610/4885NEU1 9/4885NEU4 16/4885
US-20140234912-A1 METHOD FOR GENERATING HUMAN MILK OLIGOSACCHARIDES (HMOs) OR PRECURSORS THEREOF LCT, B4GALT1, GALNT1 L3MBTL1 460/4885NEU1 63/4885NEU4 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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