Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | NPY4R | P50391 | 2/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771849 | 0.78 | KDR (0.36) | METKDRFOLH1ADAM17MAOB | |
| SCHEMBL1767417 | 0.76 | TDP1 (0.44) | POLB | |
| SCHEMBL1193133 | 0.71 | TDP1 (0.39) | POLB | |
| SCHEMBL6748044 | 0.70 | KDR (0.44) | ACEKDRFOLH1ADAM17MAOB | |
| SCHEMBL9074200 | 0.66 | ACE (0.56) | ACEFOLH1 | |
| SCHEMBL6933429 | 0.64 | KDM4E (0.68) | MAOBTP53POLB | |
| SCHEMBL11688646 | 0.62 | ALDH1A1 (0.52) | MMP2MMP9MMP8POLB | |
| SCHEMBL5010177 | 0.61 | ALDH1A1 (0.77) | POLB | |
| SCHEMBL112098 | 0.61 | ALDH1A1 (0.77) | POLB | |
| SCHEMBL5287723 | 0.60 | ADAM17 (0.81) | ADAM17MAOBMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289970-B1 | Biocompatible polymers | BARRITAULT DENIS (FR) | 2015-05-20 | — | — | EP | disclosed |
| EP-1117695-B1 | BIOCOMPATIBLE POLYMERS, COMPOSITIONS CONTAINING SAME AND THEIR USE FOR THE MANUFACTURE OF DRUGS | BARRITAULT DENIS (FR) | 2015-05-20 | — | — | EP | disclosed |
| US-8883715-B2 | Biocompatible polymers, process for their preparation and compositions containing them | BARRITAULT DENIS (FR) | 2014-11-11 | — | — | US | disclosed |
| US-20130287725-A1 | BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BARRITAULT DENIS (FR) | 2013-10-31 | — | — | US | disclosed |
| US-8476220-B2 | Biocompatible polymers, process for their preparation and compositions containing them | BARRITAULT DENIS (FR) | 2013-07-02 | — | — | US | disclosed |
| US-20110243881-A1 | BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BARRITAULT DENIS | 2011-10-06 | — | — | US | disclosed |
| US-7998922-B2 | Process for treating fibroses with biocompatible polymer | BARRITAULT DENIS | 2011-08-16 | — | — | US | disclosed |
| EP-2289970-A1 | Biocompatible polymers, their process of manufacture and compositions containing them | Barritault, Denis (FR) | 2011-03-02 | — | — | EP | disclosed |
| US-20090012040-A1 | BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BARRITAULT DENIS | 2009-01-08 | — | — | US | disclosed |
| US-20040131583-A1 | Therapy, medical diagnosis; cardiovascular disorders, central nervous system disorders, liver disorders, brain disorders; oxidation resistance | BARRITAULT DENIS (FR) | 2004-07-08 | — | — | US | disclosed |
| US-6689741-B2 | DRUGS, MEDICAL DIAGNOSIS | BARRITAULT DENIS (FR) | 2004-02-10 | — | — | US | disclosed |
| US-20010021758-A1 | Drugs, medical diagnosis | BARRITAULT DENIS (FR) | 2001-09-13 | — | — | US | disclosed |