Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279228 | 0.80 | MAOB (0.50) | ALDH1A1PKMMAOBMAOAPOLB | |
| Succinic Acid SCHEMBL8342024 | 0.76 | NPC1 (0.45) | KDRALDH1A1MAOBMAOAL3MBTL1 | |
| SCHEMBL1508356 | 0.70 | MET (0.40) | KDRFOLH1ACEMAOBAKR1B10 | |
| SCHEMBL2332848 | 0.67 | OPRM1 (0.47) | KDR | |
| SCHEMBL7227994 | 0.66 | MME (0.56) | ALDH1A1FOLH1ACEL3MBTL1MEN1 | |
| Tyrosine SCHEMBL9175478 | 0.66 | KDR (0.46) | KDRALDH1A1PKMMAOBMAOA | |
| SCHEMBL112098 | 0.66 | ALDH1A1 (0.77) | ALDH1A1PKML3MBTL1POLBMEN1 | |
| SCHEMBL5010177 | 0.66 | ALDH1A1 (0.77) | ALDH1A1PKML3MBTL1POLBMEN1 | |
| SCHEMBL5580983 | 0.65 | MAOB (0.44) | ALDH1A1PKMMAOBMAOAAKR1B10 | |
| Phenylalanine SCHEMBL5935120 | 0.65 | MAOB (0.39) | ALDH1A1PKMMAOBMAOAAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773991-B1 | ACTIVE CALPAIN EXPRESSED BY BACULOVIRUS | CEPHALON INC (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6057143-A | FOR EXPRESSION IN INSECT CELLS; TO SCREEN ENZYME INHIBITORS; AS MEAT TENDERIZER | CEPHALON, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| US-5869336-A | INSECT CELL VIRAL EXPRESSION SYSTEM PRODUCING CALCIUM ACTIVATED NEUTRAL PROTEASE; TREATMENT OF ALZHEIMER'S, HUNTINGTON'S, PARKINSON'S, MUSCULAR DYSTROPHY AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS | CEPHALON, INC. (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0773991-A1 | ACTIVE CALPAIN EXPRESSED BY BACULOVIRUS | CEPHALON, INC. (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002634-A1 | ACTIVE CALPAIN EXPRESSED BY BACULOVIRUS | CEPHALON, INC. (US) | 1996-02-01 | — | — | WO | disclosed |