Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.41 |
| ▸ | HTR6 | P50406 | 5/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16844842 | 0.82 | HTR6 (0.38) | TLR9TLR7HTR6HRH3CTSS | |
| SCHEMBL16844846 | 0.79 | TLR9 (0.36) | TLR9TLR7SUV39H2HRH3 | |
| SCHEMBL15086359 | 0.79 | HRH3 (0.39) | TLR9TLR7HTR6HRH3CTSS | |
| SCHEMBL15086252 | 0.75 | SYK (0.37) | — | |
| SCHEMBL16669761 | 0.75 | RAB9A (0.55) | TLR9TLR7HTR6SUV39H2HRH3 | |
| SCHEMBL15086464 | 0.74 | — | — | |
| SCHEMBL15086290 | 0.74 | ADRA2A (0.33) | SUV39H2 | |
| SCHEMBL15086289 | 0.74 | HTR6 (0.37) | HTR6HRH3CTSSADCY5OGG1 | |
| SCHEMBL15086519 | 0.74 | HRH3 (0.36) | HTR6HRH3 | |
| SCHEMBL21301225 | 0.72 | HTR6 (0.38) | TLR9TLR7HTR6SUV39H2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013101974-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |