Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537236 | 0.83 | MEN1 (0.58) | MEN1KMT2ACYP2C9TDP1CYP1A2 | |
| SCHEMBL2583091 | 0.59 | CYP2C9 (1.00) | MEN1KMT2ACYP2C9TDP1CYP1A2 | |
| SCHEMBL30516131 | 0.59 | CYP2C9 (1.00) | MEN1KMT2ACYP2C9TDP1CYP1A2 | |
| SCHEMBL6769896 | 0.59 | TP53 (0.54) | MEN1KMT2AKDM4ELMNAOPRL1 | |
| SCHEMBL7607540 | 0.58 | GPR3 (0.54) | KMT2ATDP1CYP1A2CYP3A4KDM4E | |
| SCHEMBL25149031 | 0.57 | LMNA (1.00) | MEN1KMT2ACYP2C9CYP3A4ATM | |
| SCHEMBL1017795 | 0.57 | CYP3A4 (0.89) | MEN1KMT2ACYP2C9TDP1CYP3A4 | |
| SCHEMBL4654592 | 0.57 | KMT2A (0.65) | MEN1KMT2ALMNAPOLBNPC1 | |
| SCHEMBL3655566 | 0.57 | DEGS1 (0.65) | MEN1KMT2AKDM4ELMNAPOLB | |
| SCHEMBL1458777 | 0.57 | CHRNB2 (0.63) | MEN1KMT2ACYP2C9CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | LRP6, BMP6, WNT3A | MEN1 3827/4885KMT2A 4661/4885CYP2C9 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.