Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TST | Q16762 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021740 | 0.98 | ALDH1A1 (0.55) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL5832861 | 0.98 | ALDH1A1 (0.55) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL186428 | 0.98 | ALDH1A1 (0.55) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1020215 | 0.98 | ALDH1A1 (0.55) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL769086 | 0.94 | CA2 (0.47) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL3289628 | 0.85 | THRB (0.47) | ALDH1A1LMNATHRBKMT2ALPL | |
| SCHEMBL15024796 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL13564090 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL19220749 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL475118 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102478-B | Preparation method of 1, 4-dicarbonyl thiosemicarbazide compound and anti-infection application | 中国医学科学院药物研究所 | 2025-04-15 | — | — | CN | disclosed |
| CN-119639383-A | Light-converting adhesive film composition | 上海海优威新材料股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119569754-A | Thiophene pyrrole fused benzothiadiazole dichroic dye and application thereof | 西安工业大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-118388973-A | Benzotriazole dichroic dye and application thereof | 西安近代化学研究所 | 2024-07-26 | — | — | CN | disclosed |
| CN-117285523-A | Apigenin derivative and application thereof in resisting tumors | 中南大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-115160277-B | Apigenin derivative and application thereof | 中南大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-116102478-A | Preparation method of 1, 4-dicarbonyl thiosemicarbazide compound and anti-infection application | 中国医学科学院药物研究所 | 2023-05-12 | — | — | CN | disclosed |
| EP-2931838-B1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| EP-1731493-A1 | BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 2006-12-13 | — | — | EP | disclosed |
| WO-2006086488-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-2005123668-A1 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-12-29 | — | — | WO | disclosed |
| EP-1565459-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | Pharmacia Corporation (US) | 2005-08-24 | — | — | EP | disclosed |
| US-20040142979-A1 | Heteroarylsulfonylmethyl hydroxamic acids and amides and their use as protease inhibitors | PHARMACIA CORPORATION | 2004-07-22 | — | — | US | disclosed |
| WO-2004048368-A2 | HETEROARYLSULFONYLMETHYL HYDROXAMIC ACIDS AND AMIDES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2004-06-10 | — | — | WO | disclosed |
| EP-0445257-B1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5204477-A | PYRIDINE DERIVATIVES IN LIQUID CRYSTALLINE MEDIUM USEFUL FOR ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0445257-A1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |
| WO-1991004249-A1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | LASP1, VCL, NEFM | ALDH1A1 4616/4885ESR1 4553/4885ADRA2A 2768/4885 |
| US-20040142979-A1 | Heteroarylsulfonylmethyl hydroxamic acids and amides and their use as protease inhibitors | MMP3, MMP13, MMP10 | ALDH1A1 1789/4885ESR1 3555/4885ADRA2A 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.