Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28726420 | 0.82 | ADA (0.42) | SMYD3LMNAUSP30TSHR | |
| SCHEMBL3689829 | 0.82 | PLA2G4A (0.40) | PLA2G4AKDM4ESMYD3RBP4KDM5A | |
| SCHEMBL3690823 | 0.80 | PLA2G4A (0.39) | PLA2G4AKDM4ESMYD3RBP4KDM5A | |
| SCHEMBL151394 | 0.80 | SMYD3 (0.50) | PLA2G4AKDM4ESMYD3RBP4KDM5A | |
| SCHEMBL4590582 | 0.80 | PLA2G4A (0.42) | PLA2G4AKDM4ESMYD3RBP4KDM5A | |
| SCHEMBL31650910 | 0.79 | PLA2G4A (0.37) | PLA2G4AKDM4ESMYD3RBP4KDM5A | |
| SCHEMBL7265607 | 0.78 | PLA2G4A (0.39) | PLA2G4AKDM4ESMYD3RBP4KDM5A | |
| SCHEMBL5730751 | 0.78 | SMYD3 (0.43) | SMYD3USP30 | |
| SCHEMBL4891287 | 0.78 | MEN1 (0.44) | KDM4ESMYD3L3MBTL1 | |
| SCHEMBL710279 | 0.77 | KDM5A (0.54) | PLA2G4AKDM4ESMYD3KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242656-A1 | N-Substituted-N-Sulfonylaminocyclopropane Compounds and Pharmaceutical Use Thereof | JAPAN TOBACCO INC. | 2008-10-02 | — | — | US | disclosed |
| US-20050222146-A1 | N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242656-A1 | N-Substituted-N-Sulfonylaminocyclopropane Compounds and Pharmaceutical Use Thereof | MMP13, MMP11, MMP3 | PLA2G4A 1199/4885KDM4E 2523/4885SMYD3 1003/4885 |
| US-20050222146-A1 | N-substituted-n-sulfonylaminocyclopropane compounds and pharmaceutical use thereof | MMP13, MMP11, MMP1 | PLA2G4A 1174/4885KDM4E 2481/4885SMYD3 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.