Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590200 | 0.82 | RBP4 (0.35) | PLA2G4AL3MBTL1RBP4KDM5AKDM5B | |
| SCHEMBL3689829 | 0.82 | PLA2G4A (0.40) | PLA2G4AKDM4EP4HTMLMNANAPRT | |
| SCHEMBL4901656 | 0.80 | PLA2G4A (0.39) | PLA2G4AKDM4EP4HTMLMNANAPRT | |
| SCHEMBL3690823 | 0.80 | PLA2G4A (0.39) | PLA2G4AKDM4EP4HTMLMNANAPRT | |
| SCHEMBL151394 | 0.80 | SMYD3 (0.50) | PLA2G4AKDM4ELMNAL3MBTL1RBP4 | |
| SCHEMBL25235849 | 0.79 | CPB2 (0.47) | PLA2G4AKDM4EKDM5AKDM5BSMYD3 | |
| SCHEMBL7265607 | 0.78 | PLA2G4A (0.39) | PLA2G4AKDM4ERBP4KDM5AKDM5B | |
| SCHEMBL3688462 | 0.78 | KDM4C (0.57) | RBP4KDM5AKDM5BTSHRKDM4C | |
| SCHEMBL710279 | 0.77 | KDM5A (0.54) | PLA2G4AKDM4ELMNAL3MBTL1KDM5A | |
| SCHEMBL24035826 | 0.76 | PLA2G4A (0.37) | PLA2G4AKDM4ERBP4KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| EP-1869019-A1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | Pfizer Products Incorporated (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006106425-A1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | disclosed |