Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392934 | 0.85 | THRB (0.51) | LMNATHRBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL134546 | 0.83 | LMNA (0.50) | LMNATHRBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9081470 | 0.82 | LMNA (0.61) | LMNATHRBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2387797 | 0.81 | LMNA (0.52) | LMNATHRBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17662334 | 0.81 | LMNA (0.52) | LMNATHRBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5427071 | 0.79 | LMNA (0.50) | LMNATHRBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9532705 | 0.79 | TAAR1 (0.52) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL7987983 | 0.78 | LMNA (0.55) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL23894744 | 0.78 | LMNA (0.57) | LMNATHRBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6794454 | 0.77 | LMNA (0.55) | LMNATHRBSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416090-B2 | Polymeric biomaterials derived from phenolic monomers and their medical uses | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-08-16 | — | — | US | disclosed |
| US-20130203713-A1 | POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203713-A1 | POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES | TH, TYR, MYB | LMNA 2860/4885THRB 3226/4885SMN1; SMN2 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.