SCHEMBL3392934

SCHEMBL3392934

C=COCCc1ccc(OC(C)=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.51
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
PTGS2 P35354 1/20 0.43
MAPT P10636 3/20 0.42
POLB P06746 1/20 0.42
PKM P14618 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TTR P02766 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ELANE P08246 1/20 0.41
HSD17B10 Q99714 1/20 0.40
ESR1 P03372 1/20 0.40
PGR P06401 1/20 0.40
CHRM2 P08172 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15164352 0.85 LMNA (0.47) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL17662334 0.83 LMNA (0.52) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL3392420 0.81 THRB (0.60) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL9081470 0.80 LMNA (0.61) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL9132980 0.80 THRB (0.54) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL2387797 0.80 LMNA (0.52) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL5836815 0.78 THRB (0.34) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL5538274 0.78 LMNA (0.53) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL23894744 0.77 LMNA (0.57) THRBLMNASMN1; SMN2NPC1RAB9A
SCHEMBL19543350 0.77 SMN1; SMN2 (0.49) THRBLMNASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056671-A1 POLYFUNCTIONAL EPOXY OLIGOMERS DESIGNER MOLECULES, INC. (US) 2010-03-04 US claimed
WO-2008128209-A1 POLYFUNCTIONAL EPOXY OLIGOMERS DESIGNER MOLECULES, INC. (US) 2008-10-23 WO claimed
US-20130299747-A1 CURATIVES FOR EPOXY COMPOSITIONSERS DESIGNER MOLECULES, INC. 2013-11-14 US disclosed
US-20130299747-A1 CURATIVES FOR EPOXY COMPOSITIONSERS DESIGNER MOLECULES, INC. 2013-11-14 US disclosed
US-20130199724-A1 CURATIVES FOR EPOXY COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2013-08-08 US disclosed
US-20130199724-A1 CURATIVES FOR EPOXY COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2013-08-08 US disclosed
US-8431655-B2 Curatives for epoxy compositions DESIGNER MOLECULES, INC. (US) 2013-04-30 US disclosed
US-8431655-B2 Curatives for epoxy compositions DESIGNER MOLECULES, INC. (US) 2013-04-30 US disclosed
US-20100249276-A1 CURATIVES FOR EPOXY COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2010-09-30 US disclosed
US-20100249276-A1 CURATIVES FOR EPOXY COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2010-09-30 US disclosed
US-20100113643-A1 CURATIVES FOR EPOXY ADHESIVE COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2010-05-06 US disclosed
US-20100113643-A1 CURATIVES FOR EPOXY ADHESIVE COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2010-05-06 US disclosed
US-20100056671-A1 POLYFUNCTIONAL EPOXY OLIGOMERS DESIGNER MOLECULES, INC. (US) 2010-03-04 US disclosed
WO-2008128209-A1 POLYFUNCTIONAL EPOXY OLIGOMERS DESIGNER MOLECULES, INC. (US) 2008-10-23 WO disclosed
WO-2008124797-A1 CURATIVES FOR EPOXY COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2008-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249276-A1 CURATIVES FOR EPOXY COMPOSITIONS ALOX5, LTC4S, ALOX15B THRB 4681/4885LMNA 3810/4885SMN1; SMN2 3254/4885
US-20100113643-A1 CURATIVES FOR EPOXY ADHESIVE COMPOSITIONS ALOX5, LTC4S, ALOX15B THRB 4724/4885LMNA 3667/4885SMN1; SMN2 3101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.