Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038913 | 1.00 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL10038904 | 1.00 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL15213587 | 0.98 | PDK2 (0.38) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL15183781 | 0.98 | PDK2 (0.38) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL21558976 | 0.97 | PDK2 (0.38) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL24750420 | 0.97 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL15214001 | 0.97 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL15213998 | 0.97 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL29444068 | 0.97 | PDK2 (0.39) | PDK2KDM4EMEN1LMNAMAPT | |
| SCHEMBL25563542 | 0.96 | PDK2 (0.40) | PDK2KDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117836-A1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-07-12 | — | — | US | disclosed |
| US-10944056-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20200235305-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-23 | — | — | US | disclosed |
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| EP-3101088-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-29 | — | — | EP | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| EP-3235892-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-3101088-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2016-12-07 | — | — | EP | disclosed |
| EP-2814906-B1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-10-19 | — | — | EP | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| WO-2013120577-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | PDK2 1024/4885KDM4E 3061/4885MEN1 331/4885 |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | PKD1, PIEZO1, AQP1 | PDK2 233/4885KDM4E 4609/4885MEN1 500/4885 |
| US-20200235305-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PKD1, PIEZO1, AQP1 | PDK2 283/4885KDM4E 4428/4885MEN1 541/4885 |
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | OCIAD2, AOC2, OCIAD1 | PDK2 741/4885KDM4E 1802/4885MEN1 1852/4885 |
| US-10944056-B2 | Materials for organic electroluminescent devices | PIEZO1, TMEM109, EPN1 | PDK2 448/4885KDM4E 4050/4885MEN1 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.