Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 9/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24646690 | 0.97 | PDK2 (0.36) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL25496136 | 0.96 | PDK2 (0.35) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL17740727 | 0.96 | KDM4E (0.36) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL23666558 | 0.94 | PDK2 (0.38) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL25496156 | 0.94 | PDK2 (0.38) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL19218265 | 0.92 | PDK2 (0.31) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL26369353 | 0.92 | PDK2 (0.35) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL25496140 | 0.91 | PDK2 (0.39) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL20710331 | 0.91 | PDK2 (0.39) | KDM4EMAPTMEN1LMNAOPRK1 | |
| SCHEMBL20710355 | 0.91 | PDK2 (0.39) | KDM4EMAPTMEN1LMNAOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117836-A1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-07-12 | — | — | US | disclosed |
| US-10944056-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20200235305-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-23 | — | — | US | disclosed |
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-01-18 | — | — | US | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9812648-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| EP-3235892-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-2814906-B1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-10-19 | — | — | EP | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-20150065730-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| WO-2013120577-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180019405-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | KDM4E 3061/4885MAPT 1878/4885MEN1 331/4885 |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | PKD1, PIEZO1, AQP1 | KDM4E 4609/4885MAPT 2733/4885MEN1 500/4885 |
| US-20200235305-A1 | SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PKD1, PIEZO1, AQP1 | KDM4E 4428/4885MAPT 2656/4885MEN1 541/4885 |
| US-20230159434-A1 | MATERIALS FOR ELECTRONIC DEVICES | OCIAD2, AOC2, OCIAD1 | KDM4E 1802/4885MAPT 731/4885MEN1 1852/4885 |
| US-10944056-B2 | Materials for organic electroluminescent devices | PIEZO1, TMEM109, EPN1 | KDM4E 4050/4885MAPT 2692/4885MEN1 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.