Bromochlorosalicylanilide

Bromochlorosalicylanilide

SCHEMBL152257

O=C(Nc1ccc(Cl)cc1)c1cc(Br)ccc1O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 7/20 0.77
NPC1 O15118 1/20 0.67
ALDH1A1 P00352 1/20 0.67
LMNA P02545 1/20 0.67
GAA P10253 1/20 0.67
RAB9A P51151 1/20 0.67
KMT2A Q03164 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
PLAU P00749 2/20 0.66
F2 P00734 1/20 0.66
F10 P00742 1/20 0.66
PLAT P00750 1/20 0.66
ALOX15 P16050 1/20 0.64
TMPRSS4 Q9NRS4 8/20 0.63
P2RX4 Q99571 4/20 0.60
P2RX7 Q99572 4/20 0.60
KCNMA1 Q12791 1/20 0.60
SLC10A2 Q12908 1/20 0.60
SLC10A1 Q14973 1/20 0.60
SLC10A6 Q3KNW5 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11683279 0.91 P2RX1 (0.82) P2RX1NPC1ALDH1A1LMNAGAA
Dibromsalan SCHEMBL29496335 0.90 PLAU (0.73) P2RX1NPC1ALDH1A1LMNAGAA
Dibromsalan SCHEMBL646973 0.90 PLAU (0.73) P2RX1NPC1ALDH1A1LMNAGAA
SCHEMBL331484 0.88 P2RX1 (0.74) P2RX1KMT2APLAUF2F10
SCHEMBL29454776 0.87 P2RX1 (1.00) P2RX1KMT2ATMPRSS4P2RX4P2RX7
SCHEMBL2169619 0.87 P2RX1 (1.00) P2RX1KMT2ATMPRSS4P2RX4P2RX7
SCHEMBL331504 0.85 HDAC3 (0.62) P2RX1NPC1LMNARAB9AKMT2A
Dibromsalan SCHEMBL29211119 0.84 PLAU (0.66) P2RX1NPC1ALDH1A1LMNARAB9A
SCHEMBL330113 0.84 TMPRSS4 (0.67) P2RX1NPC1LMNARAB9AKMT2A
SCHEMBL30343477 0.84 TMPRSS4 (0.67) P2RX1NPC1LMNARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091043-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS DATA2DISCOVERY INC (US) 2026-04-02 US claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20240173512-A1 METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS STREETERVILLE CAPITAL, LLC 2024-05-30 US claimed
EP-4374848-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION Shanghai Bao Pharmaceuticals Co., Ltd. (CN) 2024-05-29 EP claimed
WO-2024064209-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS DATA2DISCOVERY, INC. (US) 2024-03-28 WO claimed
US-11890421-B2 Methods for potentiating antimicrobial agents BEYOND AIR LTD (IL) 2024-02-06 US claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
CN-113274399-B Nystatin and quality detection method thereof 北京金城泰尔制药有限公司 2023-03-07 CN claimed
WO-2001037890-A1 A PROPELLANT FREE SPRAY-ON SKIN PATCH COMPOSITION FOR IMPROVING WOUND HEALING AND FOR DRUG ADMINISTRATION EVER POWER HOLDING INC (VG) 2001-05-31 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5811078-A IN A SOLVENT MIXTURE WITH ETHYL OR ISOPROPYL ALCOHOL AND WATER ADOLOR CORPORATION (US) 1998-09-22 US claimed
EP-0852494-A2 PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-07-15 EP claimed
WO-1997009973-A2 PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-03-20 WO claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-3956510-A NESTING, CYLINDERS, LOOPS BEALL NELSON J 1976-05-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB P2RX1 2301/4885NPC1 105/4885ALDH1A1 2722/4885
US-20260091043-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS AHCY, MACO1, ME3 P2RX1 2635/4885NPC1 427/4885ALDH1A1 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.