Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388410 | 1.00 | TSHR (0.39) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL15388541 | 1.00 | TSHR (0.39) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL15260571 | 0.90 | ADRA2A (0.37) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL15282788 | 0.90 | ADRA2A (0.37) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL12860828 | 0.90 | ADRA2A (0.37) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL817110 | 0.89 | — | — | |
| SCHEMBL28931986 | 0.87 | — | — | |
| SCHEMBL13886400 | 0.85 | NAAA (0.41) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL17547565 | 0.85 | NAAA (0.41) | TSHRADRA2AADRA1AMAPTBLM | |
| Ethylene SCHEMBL3385945 | 0.84 | TSHR (0.48) | TSHRADRA2AADRA1AMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9114328-B2 | Reactive distillation of a carboxylic acid and a glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-08-25 | — | — | US | disclosed |
| US-9114328-B2 | Reactive distillation of a carboxylic acid and a glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-08-25 | — | — | US | disclosed |
| US-9114328-B2 | Reactive distillation of a carboxylic acid and a glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-08-25 | — | — | US | disclosed |
| US-8969632-B2 | Passivation of a homogeneous hydrogenation catalyst for the production of ethylene glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| EP-2828229-A1 | PASSIVATION OF A HOMEGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | Eastman Chemical Company (US) | 2015-01-28 | — | — | EP | disclosed |
| US-20130310598-A1 | Reactive Distillation of a Carboxylic Acid and a Glycol | EASTMAN CHEMICAL COMPANY (US) | 2013-11-21 | — | — | US | disclosed |
| US-20130310598-A1 | Reactive Distillation of a Carboxylic Acid and a Glycol | EASTMAN CHEMICAL COMPANY (US) | 2013-11-21 | — | — | US | disclosed |
| US-20130253230-A1 | PASSIVATION OF A HOMOGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | EASTMAN CHEMICAL COMPANY (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2013142091-A1 | PASSIVATION OF A HOMEGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | EASTMAN CHEMICAL COMPANY (US) | 2013-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310598-A1 | Reactive Distillation of a Carboxylic Acid and a Glycol | SORD, UGCG, DGAT1 | TSHR 3784/4885ADRA2A 4160/4885ADRA1A 4171/4885 |
| US-20130253230-A1 | PASSIVATION OF A HOMOGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | HPD, TALDO1, GRHPR | TSHR 629/4885ADRA2A 2244/4885ADRA1A 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.