Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439677 | 0.89 | TSHR (0.38) | CYP11B1CYP11B2TSHRGAAACACB | |
| SCHEMBL2248952 | 0.84 | TSHR (0.47) | TSHRGAAACACB | |
| SCHEMBL28363345 | 0.82 | ALDH1A1 (0.36) | CYP11B1CYP11B2TSHRGAAACACB | |
| SCHEMBL21126224 | 0.82 | TSHR (0.42) | TSHR | |
| SCHEMBL28359952 | 0.80 | LMNA (0.47) | TSHR | |
| SCHEMBL19186 | 0.79 | JMJD6 (0.44) | TSHRGAA | |
| SCHEMBL28359954 | 0.79 | TSHR (0.42) | TSHR | |
| SCHEMBL596089 | 0.76 | GAA (0.40) | GAAACACB | |
| SCHEMBL28359973 | 0.75 | PAX8 (0.48) | GAA | |
| SCHEMBL15282392 | 0.75 | CYP3A4 (0.46) | TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130253225-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | SYNGENTA LIMITED (GB) | 2013-09-26 | — | — | US | disclosed |
| US-20130253225-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | SYNGENTA LIMITED (GB) | 2013-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253225-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | CFH, C5, CFB | CYP11B1 1918/4885CYP11B2 1336/4885TSHR 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.