Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447137 | 0.88 | KMT2A (0.42) | LGALS8ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL15280895 | 0.83 | FGF1 (0.39) | ALDH1A1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL12919676 | 0.77 | L3MBTL1 (0.39) | LGALS8L3MBTL1SLC6A2 | |
| SCHEMBL16248755 | 0.76 | ALDH1A1 (0.45) | LGALS8ALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL12564362 | 0.76 | HTT (0.46) | ALDH1A1MAPK1L3MBTL1NAAATSHR | |
| SCHEMBL12919667 | 0.76 | L3MBTL1 (0.43) | LGALS8ALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL14330356 | 0.76 | NT5E (0.42) | L3MBTL1SLC6A2 | |
| SCHEMBL4404459 | 0.74 | SLC6A2 (0.40) | LGALS8SLC6A2 | |
| SCHEMBL16640651 | 0.74 | SLC6A2 (0.40) | LGALS8SLC6A2 | |
| SCHEMBL9604424 | 0.74 | ALDH1A1 (0.42) | LGALS8ALDH1A1MAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160017015-A1 | GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160017015-A1 | GLYCO-MODIFIED ATRIAL NATRIURETIC PEPTIDE | NPPA, NPR1, NPR3 | LGALS8 276/4885ALDH1A1 2820/4885MAPK1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.