Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24543429 | 0.86 | ALDH1A1 (0.39) | RAB9AALDH1A1KMT2ATSHRPOLB | |
| SCHEMBL22491754 | 0.84 | RAB9A (0.40) | RAB9AALDH1A1KMT2ATSHRTHRB | |
| SCHEMBL296739 | 0.84 | RAB9A (0.40) | RAB9AALDH1A1KMT2ATSHRTHRB | |
| SCHEMBL15320257 | 0.84 | RAB9A (0.40) | RAB9AALDH1A1KMT2AMEN1FFAR1 | |
| SCHEMBL16534919 | 0.80 | UGT2B17 (0.42) | RAB9AALDH1A1KMT2ATSHRPOLB | |
| SCHEMBL16535044 | 0.78 | TSHR (0.39) | RAB9AALDH1A1KMT2ATSHRTHRB | |
| SCHEMBL2730679 | 0.77 | TSHR (0.34) | RAB9AALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL16534632 | 0.76 | POLL (0.38) | ALDH1A1TSHRGAACYP2C19CYP2C9 | |
| SCHEMBL16534633 | 0.76 | POLL (0.38) | ALDH1A1TSHRGAACYP2C19CYP2C9 | |
| SCHEMBL22491683 | 0.75 | ADRA2A (0.45) | ALDH1A1KMT2ATSHRMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834233-B1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | ORION CORP (FI) | 2018-04-25 | — | — | EP | disclosed |
| US-9249127-B2 | Alpha2 adrenoceptor agonists | ORION CORPORATION (FI) | 2016-02-02 | — | — | US | disclosed |
| US-20150065550-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | ORION CORPORATION (FI) | 2015-03-05 | — | — | US | disclosed |
| EP-2834233-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | Orion Corporation (FI) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013150173-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | ORION CORPORATION (FI) | 2013-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065550-A1 | NEW ALPHA2 ADRENOCEPTOR AGONISTS | ADRA2A, ADRB2, ADRA2C | RAB9A 1570/4885ALDH1A1 465/4885KMT2A 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.