Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL153246 | 1.00 | MEN1 (0.31) | MEN1KMT2ATP53MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6833667 | 0.75 | SIGMAR1 (0.33) | MEN1KMT2ATP53SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL2118673 | 0.74 | SIGMAR1 (0.31) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL2115117 | 0.73 | HTR6 (0.32) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL153247 | 0.72 | SIGMAR1 (0.30) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1655211 | 0.72 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL7129627 | 0.71 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL7722031 | 0.71 | SIGMAR1 (0.30) | SIGMAR1 | |
| Fluoride Ion SCHEMBL1130628 | 0.70 | HTR6 (0.32) | SIGMAR1 | |
| SCHEMBL21240883 | 0.70 | SIGMAR1 (0.30) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137366-A1 | Organometal compound catalyst | MCDANIEL MAX P (US) | 2005-06-23 | — | — | US | claimed |
| US-6858687-B2 | Catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer. This invention also provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer, | PHILLIPS PETROLEUM COMPANY (US) | 2005-02-22 | — | — | US | claimed |
| US-6548441-B1 | Polymerization catalysts comprises an organometal compound, an organoaluminum compound, and a halogenated nickel solid oxide compound; heterogeneous catalysts can lead to form uniform polymer particles that have a high bulk density | PHILLIPS PETROLEUM COMPANY | 2003-04-15 | — | — | US | claimed |
| US-6548442-B1 | Polymerization catalysts comprises an organometal compound, an organoaluminum compound, and a halogenated solid zirconium oxide compound; heterogeneous catalysts can lead to form uniform polymer particles that have a high bulk density | PHILLIPS PETROLEUM COMPANY | 2003-04-15 | — | — | US | claimed |
| EP-2443160-B1 | OLIGOMERIZATION OF ALPHA OLEFINS USING METALLOCENE-SSA CATALYST SYSTEMS AND USE OF THE RESULTANT POLYALPHAOLEFINS TO PREPARE LUBRICANT BLENDS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-08-14 | — | — | EP | disclosed |
| US-9334203-B2 | Oligomerization of alpha olefins using metallocene-SSA catalyst systems and use of the resultant polyalphaolefins to prepare lubricant blends | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2016-05-10 | — | — | US | disclosed |
| US-20140275664-A1 | Processes for Preparing Low Viscosity Lubricants | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-09-18 | — | — | US | disclosed |
| US-20130317265-A1 | Oligomerization of Alpha Olefins Using Metallocene-SSA Catalyst Systems and Use of the Resultant Polyalphaolefins to Prepare Lubricant Blends | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-11-28 | — | — | US | disclosed |
| US-20110082323-A1 | OLIGOMERIZATION OF OLEFIN WAXES USING METALLOCENE-BASED CATALYST SYSTEMS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-04-07 | — | — | US | disclosed |
| US-6548442-B1 | Polymerization catalysts comprises an organometal compound, an organoaluminum compound, and a halogenated solid zirconium oxide compound; heterogeneous catalysts can lead to form uniform polymer particles that have a high bulk density | PHILLIPS PETROLEUM COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-6548441-B1 | Polymerization catalysts comprises an organometal compound, an organoaluminum compound, and a halogenated nickel solid oxide compound; heterogeneous catalysts can lead to form uniform polymer particles that have a high bulk density | PHILLIPS PETROLEUM COMPANY | 2003-04-15 | — | — | US | disclosed |
| US-6395666-B1 | COORDINATION POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY | 2002-05-28 | — | — | US | disclosed |
| US-6391816-B1 | ROASTED ORGANOMETALLIC, ORGANOALUMINUM, AND HALOGENATED VANADIUM-CONTAINING SOLID OXIDE COMPOUNDS; ADDITION POLYMERIZATION CATALYSTS | PHILLIPS PETROLEUM | 2002-05-21 | — | — | US | disclosed |
| US-6355594-B1 | CONTACTING AT LEAST ONE ORGANOMETAL COMPOUND, AT LEAST ONE ORGANOALUMINUM COMPOUND, AND AT LEAST ONE FLUORIDED SILICA-ALUMINA TO PRODUCE POLYMERIZATION CATALYST COMPOSITION | PHILLIPS PETROLEUM COMPANY | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130317265-A1 | Oligomerization of Alpha Olefins Using Metallocene-SSA Catalyst Systems and Use of the Resultant Polyalphaolefins to Prepare Lubricant Blends | SAE1, MACO1, MSMO1 | MEN1 1273/4885KMT2A 4330/4885TP53 1289/4885 |
| US-20140275664-A1 | Processes for Preparing Low Viscosity Lubricants | TARDBP, OSTC, RAB5IF | MEN1 4468/4885KMT2A 3941/4885TP53 2975/4885 |
| US-20110082323-A1 | OLIGOMERIZATION OF OLEFIN WAXES USING METALLOCENE-BASED CATALYST SYSTEMS | SQLE, COG8, OSBPL8 | MEN1 490/4885KMT2A 4470/4885TP53 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.