Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898221 | 0.95 | CYP2D6 (0.38) | CYP2D6HIF1ACYP2C9GABRA1GABRB2 | |
| SCHEMBL16259555 | 0.93 | GABRA1 (0.44) | CYP2D6HIF1ACYP2C9GABRA1GABRB2 | |
| SCHEMBL16259688 | 0.89 | AR (0.39) | ALDH1A1PDE2A | |
| SCHEMBL23113724 | 0.85 | HIF1A (0.34) | CYP2D6HIF1ACYP2C9GABRA1GABRB2 | |
| SCHEMBL10203676 | 0.85 | SLC6A3 (0.33) | CYP2D6HIF1ACYP2C9GABRA1GABRB2 | |
| SCHEMBL548187 | 0.81 | GABRA1 (0.45) | HIF1AGABRA1GABRB2CYP1A2ALDH1A1 | |
| SCHEMBL377542 | 0.79 | GABRA1 (0.48) | CYP2D6HIF1ACYP2C9GABRA1GABRB2 | |
| SCHEMBL26575146 | 0.78 | RXRA (0.35) | — | |
| SCHEMBL31095742 | 0.78 | KIF11 (0.46) | CYP2D6HIF1ACYP2C9TRPA1PTGS1 | |
| SCHEMBL3370465 | 0.78 | KIF11 (0.46) | CYP2D6HIF1ACYP2C9TRPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281742-A1 | METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES | THE UNIVERSITY OF AKRON (US) | 2013-10-24 | — | — | US | claimed |
| US-11579526-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-02-14 | — | — | US | disclosed |
| US-20200301274-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-09-24 | — | — | US | disclosed |
| US-20130281742-A1 | METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES | THE UNIVERSITY OF AKRON (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281742-A1 | METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES | THE UNIVERSITY OF AKRON (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281742-A1 | METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES | THE UNIVERSITY OF AKRON (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281742-A1 | METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES | TET1, TET3, DNMT1 | CYP2D6 1290/4885HIF1A 2128/4885CYP2C9 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.