SCHEMBL1533765

SCHEMBL1533765

CCCCCc1ccc(-c2ccc(B(O)O)c(F)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.62
RARA P10276 2/20 0.62
RARG P13631 1/20 0.62
LPL P06858 5/20 0.54
LIPG Q9Y5X9 5/20 0.54
TRPV1 Q8NER1 1/20 0.53
MGLL Q99685 1/20 0.53
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
MTOR P42345 1/20 0.48
KMT2A Q03164 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HRH3 Q9Y5N1 1/20 0.46
HSD17B10 Q99714 2/20 0.45
TSHR P16473 1/20 0.45
ESR1 P03372 2/20 0.45
ADRA2A P08913 2/20 0.45
ADORA3 P0DMS8 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955233 1.00 RARB (0.62) RARBRARARARGLPLLIPG
SCHEMBL29957265 0.98 RARB (0.64) RARBRARARARGLPLLIPG
SCHEMBL7781671 0.98 RARB (0.64) RARBRARARARGLPLLIPG
SCHEMBL29956137 0.95 RARB (0.56) RARBRARARARGLPLLIPG
SCHEMBL31028375 0.89 LPL (0.50) RARBRARARARGLPLLIPG
SCHEMBL1533780 0.89 LPL (0.50) RARBRARARARGLPLLIPG
SCHEMBL29952644 0.87 LIPG (0.56) RARBRARARARGLPLLIPG
SCHEMBL6555943 0.87 LIPG (0.56) RARBRARARARGLPLLIPG
SCHEMBL19384703 0.84 RARB (0.60) RARBRARARARGLPLLIPG
SCHEMBL28432201 0.83 LIPG (0.56) RARBRARARARGLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307575-B Synthesis method of 4' -alkyl-3-fluoro-4-biphenylboronic acid 山东盛华电子新材料有限公司 2024-08-02 CN disclosed
CN-118307575-A Synthesis method of 4' -alkyl-3-fluoro-4-biphenylboronic acid 山东盛华电子新材料有限公司 2024-07-09 CN disclosed
EP-2853523-B1 Process for producing fluorine-containing biaryl compound DAIKIN IND LTD (JP) 2018-05-30 EP disclosed
US-20180105750-A1 LIQUID CRYSTAL MATERIALS, METHODS OF FABRICATING LIQUID CRYSTAL DISPLAY PANELS AND LIQUID CRYSTAL DISPLAY PANELS SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-04-19 US disclosed
US-20160108317-A1 DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND MERCK PATENT GMBH (DE) 2016-04-21 US disclosed
EP-2853523-A1 Process for producing fluorine-containing biaryl compound Daikin Industries, Ltd. (JP) 2015-04-01 EP disclosed
WO-2014187529-A1 DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND MERCK PATENT GMBH (DE) 2014-11-27 WO disclosed
US-8394293-B2 Thiophene derivatives, and LC media containing same MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-03-12 US disclosed
EP-2265692-B1 THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME MERCK PATENT GMBH (DE) 2012-07-04 EP disclosed
US-20110049427-A1 Thiophene derivatives, and LC media containing same MERCK PATENT GESELLSCHAFT (DE) 2011-03-03 US disclosed
EP-2265692-A1 THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME Merck Patent GmbH (DE) 2010-12-29 EP disclosed
WO-2009129915-A1 THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME MERCK PATENT GMBH (DE) 2009-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160108317-A1 DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND CRY1, SLC25A1, CRY2 RARB 172/4885RARA 175/4885RARG 198/4885
US-20180105750-A1 LIQUID CRYSTAL MATERIALS, METHODS OF FABRICATING LIQUID CRYSTAL DISPLAY PANELS AND LIQUID CRYSTAL DISPLAY PANELS VCL, PI4K2A, PLK4 RARB 3287/4885RARA 1870/4885RARG 2615/4885
US-20110049427-A1 Thiophene derivatives, and LC media containing same TPMT, TEC, LCT RARB 3984/4885RARA 4056/4885RARG 4297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.