Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.53 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475478 | 0.82 | GRM5 (0.54) | GRM5ASIC3PLAUKDRMEN1 | |
| Hydrochloric Acid SCHEMBL28723284 | 0.80 | GRM5 (0.53) | GRM5ASIC3PLAUKDRMEN1 | |
| Hydrochloric Acid SCHEMBL28720176 | 0.80 | GRM5 (0.53) | GRM5ASIC3PLAUKDRMEN1 | |
| SCHEMBL22593337 | 0.80 | GRM5 (0.53) | GRM5ASIC3PLAUKDRMEN1 | |
| SCHEMBL7238803 | 0.78 | NPC1 (0.68) | GRM5MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL13562935 | 0.77 | TRPM8 (0.52) | GRM5ASIC3PLAUKDRMEN1 | |
| SCHEMBL26575932 | 0.77 | PGK1 (0.50) | GRM5ASIC3KDRGFERKDM4E | |
| SCHEMBL16571322 | 0.77 | PLAU (0.49) | GRM5ASIC3PLAUKDRMEN1 | |
| SCHEMBL19044509 | 0.77 | CYP2C9 (0.50) | GRM5MEN1KMT2AMAPTLMNA | |
| SCHEMBL25045421 | 0.76 | GRM5 (0.49) | GRM5ASIC3PLAUKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11230540-B2 | Substituted triazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-01-25 | — | — | US | disclosed |
| US-11230540-B2 | Substituted triazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-01-25 | — | — | US | disclosed |
| US-20210179590-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | US | disclosed |
| US-20210179590-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | US | disclosed |
| US-11006631-B2 | Substituted pyrimidinyloxy pyridine derivatives as herbicides | FMC CORPORATION (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200283398-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2020-09-10 | — | — | US | disclosed |
| EP-3700899-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2020-09-02 | — | — | EP | disclosed |
| US-10442777-B2 | Use of substituted oxadiazoles for combating phytopathogenic fungi | BASF SE (DE) | 2019-10-15 | — | — | US | disclosed |
| US-20190144422-A1 | HYDROXYALKYL-SUBSTITUTED HETEROARYLTRIAZOLE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2019-05-16 | — | — | US | disclosed |
| US-20190119251-A1 | AMIDE-SUBSTITUTED ARYLTRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-04-25 | — | — | US | disclosed |
| WO-2010076525-A1 | DERIVATIVES OF 2-PYRIDIN-2-YL-PYRAZOL-3(2H)-ONE, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-07-08 | — | — | WO | disclosed |
| EP-2194046-A1 | Triazolone derivative | Eisai R&D Management Co., Ltd. (JP) | 2010-06-09 | — | — | EP | disclosed |
| CN-101405275-A | Triazolone Derivatives | EISAI R&D MAN CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| EP-2000465-A1 | TRIAZOLONE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
| US-20080015199-A1 | Triazolone derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
| US-6552018-B1 | As antitumor agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| CN-1105707-C | Pyrazole derivative | DAIICHI SEIYAKU CO (JP) | 2003-04-16 | — | — | CN | disclosed |
| US-6169086-B1 | AN ANTITUMOR AGENT FOR TREATING TUMOR RESISTANT TO 5-FLUOROURACIL TYPE DRUGS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-1022270-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |
| CN-1251578-A | Pyrazole derivative | DAIICHI SEIYAKU CO (JP) | 2000-04-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179590-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | GLS, TNNI3, CYP11B2 | GRM5 2171/4885ASIC3 3038/4885PLAU 2465/4885 |
| US-11230540-B2 | Substituted triazole derivatives and uses thereof | GLS, TNNI3, CYP11B2 | GRM5 2171/4885ASIC3 3038/4885PLAU 2465/4885 |
| US-11006631-B2 | Substituted pyrimidinyloxy pyridine derivatives as herbicides | DDT, CNPY2, NOX4 | GRM5 771/4885ASIC3 1835/4885PLAU 4837/4885 |
| US-10442777-B2 | Use of substituted oxadiazoles for combating phytopathogenic fungi | CYP51A1, DPM1, NOX1 | GRM5 1713/4885ASIC3 3340/4885PLAU 4342/4885 |
| US-20190144422-A1 | HYDROXYALKYL-SUBSTITUTED HETEROARYLTRIAZOLE DERIVATIVES AND USES THEREOF | AADAC, LIPG, HHAT | GRM5 2478/4885ASIC3 2532/4885PLAU 1982/4885 |
| US-20190119251-A1 | AMIDE-SUBSTITUTED ARYLTRIAZOLE DERIVATIVES AND USES THEREOF | AADAC, NAT1, GLS | GRM5 1562/4885ASIC3 1294/4885PLAU 2712/4885 |
| US-20200283398-A1 | USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI | CYP51A1, DPM1, NOX1 | GRM5 1713/4885ASIC3 3340/4885PLAU 4342/4885 |
| US-20080015199-A1 | Triazolone derivatives | F3, F12, F2 | GRM5 4465/4885ASIC3 4186/4885PLAU 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.