Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | NAMPT | P43490 | 12/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16383044 | 0.93 | NPC1 (0.65) | HDAC1HDAC6NAMPTEPHX2NR1H4 | |
| SCHEMBL15344287 | 0.90 | NAMPT (0.56) | HDAC1HDAC6NAMPTEPHX2NR1H4 | |
| SCHEMBL15344336 | 0.89 | NAMPT (0.55) | HDAC1HDAC6NAMPTEPHX2NR1H4 | |
| SCHEMBL15344337 | 0.87 | HDAC1 (0.63) | HDAC1HDAC6NAMPTEPHX2NR1H4 | |
| SCHEMBL16383167 | 0.85 | NPC1 (0.60) | HDAC1HDAC6NAMPTNPC1ALDH1A1 | |
| SCHEMBL16383045 | 0.84 | NPC1 (0.59) | HDAC1HDAC6NAMPTNPC1ALDH1A1 | |
| SCHEMBL16383043 | 0.84 | NPC1 (0.58) | HDAC1HDAC6NPC1ALDH1A1CA1 | |
| SCHEMBL12604884 | 0.82 | HDAC1 (0.58) | HDAC1HDAC6NAMPTEPHX2NR1H4 | |
| SCHEMBL16383046 | 0.81 | NPC1 (0.71) | HDAC1HDAC6NAMPTNPC1ALDH1A1 | |
| SCHEMBL16378810 | 0.81 | NAMPT (0.67) | HDAC1HDAC6NAMPTEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084735-B2 | Self-assembling bis-urea compounds for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-07-21 | — | — | US | disclosed |
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-02-05 | — | — | US | disclosed |
| US-8921426-B2 | Cationic bis-urea compounds as effective antimicrobial agents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130281515-A1 | CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281515-A1 | CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS | NOS3, NOS1, NOS2 | HDAC1 965/4885HDAC6 685/4885NAMPT 3268/4885 |
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | SLC14A1, NONO, PUF60 | HDAC1 550/4885HDAC6 503/4885NAMPT 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.