SCHEMBL15345331

SCHEMBL15345331

NCc1cc(Oc2ccccc2)c2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 4/20 0.44
RHEB Q15382 1/20 0.43
LOX P28300 2/20 0.43
HTR2A P28223 1/20 0.43
DPP4 P27487 1/20 0.42
HRH1 P35367 1/20 0.41
TTR P02766 2/20 0.40
KCNA3 P22001 1/20 0.39
ST14 Q9Y5Y6 1/20 0.39
ASIC3 Q9UHC3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15345402 0.84 DPP4 (0.47) LOXL2LOXDPP4HRH1TTR
SCHEMBL15345666 0.79 HTR2A (0.46) HTR2A
SCHEMBL22210568 0.79 LOXL2 (0.49) LOXL2RHEBLOXDPP4HRH1
SCHEMBL15345521 0.77 TLR8 (0.44) LOXL2HTR2A
SCHEMBL6745255 0.74 GPR84 (0.49)
SCHEMBL15345463 0.74 DPP4 (0.47) LOXL2LOXDPP4HRH1TTR
SCHEMBL15345430 0.74 CSNK2A1 (0.49) HTR2A
SCHEMBL5992232 0.74 NQO2 (0.52) TTR
SCHEMBL15345404 0.73 NQO2 (0.55) LOXL2HTR2A
SCHEMBL10473118 0.72 MAPT (0.53) RHEBHTR2ADPP4HRH1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657214-B1 PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL MITSUBISHI GAS CHEMICAL CO (JP) 2017-02-15 EP disclosed
US-8993774-B2 Process for production of aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-03-31 US disclosed
US-20130303775-A1 PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-14 US disclosed
EP-2657214-A1 PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL Mitsubishi Gas Chemical Company, Inc. (JP) 2013-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303775-A1 PROCESS FOR PRODUCTION OF AROMATIC ALCOHOL OR HETEROCYCLIC AROMATIC ALCOHOL ADH1C, ADH1A, ADH5 LOXL2 3456/4885RHEB 4261/4885LOX 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.