Aniline

Aniline

SCHEMBL15366232

Brc1ccccc1-c1cccc2ccccc12.Nc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 4/20 0.42
TSHR P16473 3/20 0.42
HPGD P15428 3/20 0.42
MAPK1 P28482 2/20 0.42
CYP3A4 P08684 1/20 0.42
KEAP1 Q14145 1/20 0.42
GRM2 Q14416 1/20 0.42
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
PDE10A Q9Y233 1/20 0.40
HKDC1 Q2TB90 1/20 0.40
DHFR P00374 1/20 0.39
MAPT P10636 3/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
PRKCZ Q05513 1/20 0.39
C1R P00736 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29634644 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10TSHRHPGDMAPK1
SCHEMBL365314 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10TSHRHPGDMAPK1
Aniline SCHEMBL18260676 0.79 PRKCZ (0.47) ALDH1A1HSD17B10TSHRHPGDMAPK1
Benzene SCHEMBL28202246 0.77 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRHPGDMAPK1
Benzidine SCHEMBL7580134 0.76 PRKCZ (0.56) ALDH1A1HSD17B10TSHRHPGDCYP3A4
SCHEMBL23187820 0.75 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDMAPK1
SCHEMBL13016366 0.75 ALDH1A1 (0.58) ALDH1A1MAPK1CA12CA1CA2
SCHEMBL29350007 0.74 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRHPGDMAPK1
SCHEMBL25302086 0.74 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRHPGDMAPK1
SCHEMBL27953 0.74 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10249824-B2 Condensed-cyclic compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
CN-103382178-B Fused ring compound and Organic Light Emitting Diode comprising it 三星显示有限公司 2018-11-16 CN disclosed
EP-2666768-B1 Condensed-cyclic compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO LTD (KR) 2016-12-21 EP disclosed
EP-2940018-B1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2016-11-23 EP disclosed
EP-2940018-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME Samsung Display Co., Ltd. (KR) 2015-11-04 EP disclosed
EP-2666768-A2 Condensed-cyclic compound and organic light-emitting diode comprising the same Samsung Display Co., Ltd. (KR) 2013-11-27 EP disclosed
US-20130292653-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2013-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130292653-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME CRY1, CRY2, CCNT1 ALDH1A1 63/4885HSD17B10 1435/4885TSHR 4583/4885
US-10249824-B2 Condensed-cyclic compound and organic light-emitting diode comprising the same CRY1, CRY2, CCNT1 ALDH1A1 63/4885HSD17B10 1435/4885TSHR 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.