Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Methyl Phosphonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.62 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.62 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GGH | Q92820 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Phosphonate SCHEMBL758011 | 1.00 | GLRA1 (0.62) | GLRA1SLC6A9OR51E2CA2TSHR | |
| Glycine SCHEMBL27717185 | 0.94 | GLRA1 (0.62) | GLRA1SLC6A9OR51E2CA2TSHR | |
| Methyl Phosphonate SCHEMBL29127321 | 0.89 | GLRA1 (0.50) | GLRA1SLC6A9OR51E2CA2TSHR | |
| Methyl Phosphonate SCHEMBL28726099 | 0.87 | GLRA1 (0.48) | GLRA1SLC6A9OR51E2CA2TSHR | |
| Glycine SCHEMBL29130842 | 0.87 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2TSHRLMNA | |
| Glycine SCHEMBL1023304 | 0.87 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2TSHRLMNA | |
| Glycine SCHEMBL9274191 | 0.87 | GLRA1 (0.71) | GLRA1SLC6A9OR51E2TSHRLMNA | |
| Glycine SCHEMBL28244367 | 0.84 | GLRA1 (0.67) | GLRA1SLC6A9OR51E2TSHRLMNA | |
| Glycine SCHEMBL15419631 | 0.84 | GLRA1 (0.50) | GLRA1SLC6A9OR51E2CA2TSHR | |
| Glycine SCHEMBL28466543 | 0.82 | GLRA1 (0.56) | GLRA1SLC6A9OR51E2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9463990-B2 | Water treatment agent for removing contaminant through oxidation with highly-active manganese (V) intermediate | HARBIN INSTITUTE OF TECHNOLOGY (CN) | 2016-10-11 | — | — | US | claimed |
| US-20140021401-A1 | Water Treatment Agent for Removing Contaminant Through Oxidation with High-Activity Intermediate-State Pentavalent Manganese | HARBIN INSTITUTE OF TECHNOLOGY (CN) | 2014-01-23 | — | — | US | claimed |
| US-11779013-B2 | Stabilized peroxyacid solutions | EVONIK CORPORATION (US) | 2023-10-10 | — | — | US | disclosed |
| CN-112512320-B | Stabilized peroxyacid solutions | 赢创有限公司 | 2022-07-08 | — | — | CN | disclosed |
| US-20210363008-A1 | PROCESS FOR PREPARING A STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTION | EVONIK CORPORATION (US) | 2021-11-25 | — | — | US | disclosed |
| US-20210307332-A1 | POLYMER-STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTIONS AND ASSOCIATED METHODS | EVONIK CORPORATION (US) | 2021-10-07 | — | — | US | disclosed |
| US-20210219543-A1 | STABILIZED PEROXYACID SOLUTIONS | EVONIK CORPORATION (US) | 2021-07-22 | — | — | US | disclosed |
| US-20210206635-A1 | STABILIZED HYDROGEN PEROXIDE-CHLORATE MIXTURES | EVONIK CORPORATION (US) | 2021-07-08 | — | — | US | disclosed |
| EP-3829306-A1 | STABILIZED PEROXYACID SOLUTIONS | Evonik Corporation (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3830023-A1 | STABILIZED HYDROGEN PEROXIDE-CHLORATE MIXTURES | Evonik Corporation (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3830027-A1 | POLYMER-STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTIONS AND ASSOCIATED METHODS | Evonik Corporation (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3830026-A1 | PROCESS FOR PREPARING A STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTION | Evonik Corporation (US) | 2021-06-09 | — | — | EP | disclosed |
| CN-112533862-A | Stabilized hydrogen peroxide-chlorate mixtures | 赢创有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112512320-A | Stabilized peroxyacid solutions | 赢创有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020028657-A1 | STABILIZED PEROXYACID SOLUTIONS | EVONIK CORPORATION (US) | 2020-02-06 | — | — | WO | disclosed |
| WO-2020028655-A1 | POLYMER-STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTIONS AND ASSOCIATED METHODS | EVONIK CORPORATION (US) | 2020-02-06 | — | — | WO | disclosed |
| WO-2020028651-A1 | PROCESS FOR PREPARING A STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTION | EVONIK CORPORATION (US) | 2020-02-06 | — | — | WO | disclosed |
| WO-2020028652-A1 | STABILIZED HYDROGEN PEROXIDE-CHLORATE MIXTURES | EVONIK CORPORATION (US) | 2020-02-06 | — | — | WO | disclosed |
| US-9463990-B2 | Water treatment agent for removing contaminant through oxidation with highly-active manganese (V) intermediate | HARBIN INSTITUTE OF TECHNOLOGY (CN) | 2016-10-11 | — | — | US | disclosed |
| US-20140021401-A1 | Water Treatment Agent for Removing Contaminant Through Oxidation with High-Activity Intermediate-State Pentavalent Manganese | HARBIN INSTITUTE OF TECHNOLOGY (CN) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210307332-A1 | POLYMER-STABILIZED AQUEOUS HYDROGEN PEROXIDE SOLUTIONS AND ASSOCIATED METHODS | GPX4, PSPH, PHOSPHO1 | GLRA1 2813/4885SLC6A9 2477/4885OR51E2 4113/4885 |
| US-11779013-B2 | Stabilized peroxyacid solutions | PGD, ACMSD, ALAD | GLRA1 2340/4885SLC6A9 2329/4885OR51E2 1281/4885 |
| US-20210219543-A1 | STABILIZED PEROXYACID SOLUTIONS | PGD, ACMSD, ALAD | GLRA1 2340/4885SLC6A9 2329/4885OR51E2 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.