SCHEMBL362736

SCHEMBL362736

CC(=O)O[C@@]12[C@H](O)[C@@H](C)[C@@]3(O)[C@@H](C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1C2(C)C

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKCA P17252 5/20 0.71
▸ PRKD3 O94806 4/20 0.71
▸ PRKCG P05129 4/20 0.71
▸ PRKCB P05771 4/20 0.71
▸ PRKCH P24723 4/20 0.71
▸ PRKCI P41743 4/20 0.71
▸ PRKCE Q02156 4/20 0.71
▸ PRKCQ Q04759 4/20 0.71
▸ PRKCZ Q05513 4/20 0.71
▸ PRKCD Q05655 4/20 0.71
▸ PRKD1 Q15139 4/20 0.71
▸ USP2 O75604 2/20 0.71
▸ TP53 P04637 2/20 0.71
▸ KDM4E B2RXH2 1/20 0.71
▸ ALDH1A1 P00352 1/20 0.71
▸ SMN1; SMN2 Q16637 1/20 0.71
▸ CYP3A4 P08684 1/20 0.71
▸ CYP2C9 P11712 1/20 0.71
▸ TSHR P16473 1/20 0.71
▸ NFKB1 P19838 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21981002 1.00 PRKCA (0.71) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL18628313 1.00 PRKCA (0.71) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL15423138 1.00 PRKCA (0.71) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL18399929 1.00 PRKCA (0.71) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL16922842 1.00 PRKCA (0.71) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL30194475 1.00 PRKCA (0.71) PRKCAPRKD3PRKCGPRKCBPRKCH
Ammonia Solution, Strong SCHEMBL5508975 0.99 PRKCA (0.70) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL12925016 0.93 PRKCA (0.65) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL18399927 0.93 PTGS2 (0.64) PRKCAPRKD3PRKCGPRKCBPRKCH
SCHEMBL15423106 0.93 PTGS2 (0.64) PRKCAPRKD3PRKCGPRKCBPRKCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041660-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms CHANG RICHARD L (US) 2026-02-12 — — US claimed
US-12539289-B2 Phorbol ester compositions and methods of use for treating or reducing the duration of cytopenia BIOSUCCESS BIOTECH COMPANY, LIMITED (US) 2026-02-03 — — US claimed
EP-2804601-B1 PHORBOL ESTER compounds for use in the treatment of neoplastic diseases BIOSUCCESS BIOTECH CO LTD (US) 2025-04-02 — — EP claimed
US-20240261247-A1 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS BIOSUCCESS BIOTECH CO., LTD. (US) 2024-08-08 — — US claimed
US-20240082202-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms CHANG RICHARD L (US) 2024-03-14 — — US claimed
EP-4304570-A2 COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFLAMMATORY DISORDERS CAUSED BY CORONAVIRUSES Phor-Med, Inc. (US) 2024-01-17 — — EP claimed
CN-117015375-A Compositions and methods for treating Acute Respiratory Distress Syndrome (ARDS) and inflammatory conditions caused by coronaviruses 福尔医学公司 2023-11-07 — — CN claimed
US-20230277495-A1 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS BIOSUCCESS BIOTECH CO. LTD. (US) 2023-09-07 — — US claimed
US-20230248684-A1 COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFLAMMATORY DISORDERS CAUSED BY CORONAVIRUSES AND OTHER RESPIRATORY PATHOGENS OR AGENTS THAT MEDIATE PULMONARY INJURY, INFLAMMATION OR ACUTE RESPIRATORY DISTRESS, AND RELATED COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING HUMAN SARS CORONAVIRUS INFECTION, COVID-19 DISEASE AND RELATED SYMPTOMS PHOR-MED, INC. 2023-08-10 — — US claimed
US-11696908-B2 Compositions and methods of use of phorbol esters BIOSUCCESS BIOTECH CO. LTD. (US) 2023-07-11 — — US claimed
WO-2013110006-A2 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS BIOSUCCESS BIOTECH CO. LTD. (US) 2013-07-25 — — WO claimed
EP-2368555-A1 Compositions and methods of use of phorbolesters Biosuccess Biotech Company (US) 2011-09-28 — — EP claimed
EP-2170053-A1 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS Biosuccess Biotech Company (US) 2010-04-07 — — EP claimed
US-20080226589-A1 Such as phorbol 13-butyrate for treatment of cytopathic diseases such as HIV, AIDS, and/or neoplasms BIOSUCCESS BIOTECH CO. 2008-09-18 — — US claimed
WO-2008094657-A1 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS BIOSUCCESS BIOTECH COMPANY (US) 2008-08-07 — — WO claimed
EP-0349127-B1 ANTIBODY-MEDIATED AND LIGAND-MEDIATED TARGETING OF DIFFERENTIATION-INDUCERS TO TUMOR CELLS The Biomembrane Institute (US) 1993-09-29 — — EP claimed
EP-0108919-B1 PROCESS FOR PRODUCING T CELL-ACTIVATING FACTOR Okai, Yasuji (JP) 1988-07-13 — — EP claimed
US-4613458-A INHIBITS DNA SYNEHESIS OF T CELLS, AUTOIMMUNE DISEASES KYOWA HAKKO KOGYO CO., LTD. (JP) 1986-09-23 — — US claimed
EP-0135592-A1 DNA SYNTHESIS-REPRESSING SUBSTANCE KYOWA HAKKO KOGYO CO., LTD. (JP) 1985-04-03 — — EP claimed
EP-0108919-A2 Process for producing T cell-activating factor Okai, Yasuji (JP) 1984-05-23 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696908-B2 Compositions and methods of use of phorbol esters PMAIP1, CD38, PKD1 PRKCA 41/4885PRKD3 229/4885PRKCG 53/4885
US-20240261247-A1 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS PMAIP1, KLK3, ACP3 PRKCA 42/4885PRKD3 235/4885PRKCG 51/4885
US-20230277495-A1 COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS PMAIP1, KLK3, ACP3 PRKCA 42/4885PRKD3 235/4885PRKCG 51/4885
US-20260041660-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms TSLP, MAVS, PLAA PRKCA 32/4885PRKD3 910/4885PRKCG 102/4885
US-20080226589-A1 Such as phorbol 13-butyrate for treatment of cytopathic diseases such as HIV, AIDS, and/or neoplasms STAT6, NFATC1, BAD PRKCA 164/4885PRKD3 138/4885PRKCG 366/4885
US-12539289-B2 Phorbol ester compositions and methods of use for treating or reducing the duration of cytopenia MYD88, EBP, IL2 PRKCA 45/4885PRKD3 274/4885PRKCG 154/4885
US-20240082202-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms MAVS, ACE2, PLAA PRKCA 12/4885PRKD3 885/4885PRKCG 36/4885
US-20230248684-A1 COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFLAMMATORY DISORDERS CAUSED BY CORONAVIRUSES AND OTHER RESPIRATORY PATHOGENS OR AGENTS THAT MEDIATE PULMONARY INJURY, INFLAMMATION OR ACUTE RESPIRATORY DISTRESS, AND RELATED COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING HUMAN SARS CORONAVIRUS INFECTION, COVID-19 DISEASE AND RELATED SYMPTOMS MAVS, ACE2, CCL11 PRKCA 16/4885PRKD3 716/4885PRKCG 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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