Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444464 | 1.00 | SIGMAR1 (0.43) | SIGMAR1FKBP1ASMN1; SMN2PTGER4ALDH1A1 | |
| SCHEMBL15421166 | 0.84 | PTGER4 (0.37) | SMN1; SMN2PTGER4ALDH1A1LMNALTA4H | |
| SCHEMBL40125 | 0.83 | FKBP1A (0.53) | SIGMAR1FKBP1AALDH1A1LTA4HCYP3A4 | |
| SCHEMBL40124 | 0.83 | FKBP1A (0.53) | SIGMAR1FKBP1AALDH1A1LTA4HCYP3A4 | |
| SCHEMBL40181 | 0.81 | SIGMAR1 (0.54) | SIGMAR1FKBP1ASMN1; SMN2 | |
| SCHEMBL40182 | 0.81 | SIGMAR1 (0.54) | SIGMAR1FKBP1ASMN1; SMN2 | |
| SCHEMBL15432838 | 0.74 | PTGER4 (0.38) | SMN1; SMN2PTGER4ALDH1A1LMNALTA4H | |
| SCHEMBL45606 | 0.74 | PTGER4 (0.38) | SMN1; SMN2PTGER4ALDH1A1LMNALTA4H | |
| SCHEMBL45550 | 0.72 | SMN1; SMN2 (0.37) | FKBP1ASMN1; SMN2PTGER4ALDH1A1LMNA | |
| SCHEMBL13783440 | 0.70 | ALDH1A1 (0.48) | FKBP1ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC10A2, SLC34A2, SLC34A3 | SIGMAR1 1812/4885FKBP1A 2199/4885SMN1; SMN2 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.