Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.59 |
| ▸ | CTSS | P25774 | 7/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688825 | 1.00 | CTSK (0.59) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12808094 | 0.91 | CTSK (0.58) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1372787 | 0.91 | CTSK (0.58) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL241915 | 0.91 | CTSK (0.58) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12069015 | 0.89 | CYP1A2 (0.64) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12071191 | 0.89 | CYP1A2 (0.64) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12070120 | 0.89 | CYP1A2 (0.64) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27946249 | 0.87 | CTSK (0.55) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21423545 | 0.86 | CTSK (0.54) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16473197 | 0.86 | CTSK (0.54) | CTSKCTSSCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926298-B2 | Heterocyclic compounds and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2018-03-27 | — | — | US | disclosed |
| US-20180009786-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RES INST (TW) | 2018-01-11 | — | — | US | disclosed |
| US-9862703-B2 | Heterocyclic compounds and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2018-01-09 | — | — | US | disclosed |
| US-9556119-B2 | Process for preparing desmosine, isodesmosine, and derivatives thereof | SOPHIA SCHOOL CORPORATION (JP) | 2017-01-31 | — | — | US | disclosed |
| US-20160083369-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | NAT HEALTH RESEARCH INSTITUTES (TW) | 2016-03-24 | — | — | US | disclosed |
| US-20150376127-A1 | PROCESS FOR PREPARING DESMOSINE, ISODESMOSINE, AND DERIVATIVES THEREOF | SOPHIA SCHOOL CORPORATION (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2379540-B1 | DIPEPTOID PRODRUGS AND THE USE THEREOF | BAYER IP GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2687511-A1 | Pyridinone derivatives as tissue transglutaminase inhibitors | Zedira GmbH (DE) | 2014-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009786-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | CXCL12, HPGDS, MCL1 | CTSK 2763/4885CTSS 2739/4885CYP1A2 715/4885 |
| US-20150376127-A1 | PROCESS FOR PREPARING DESMOSINE, ISODESMOSINE, AND DERIVATIVES THEREOF | SI, SMS, SRM | CTSK 1451/4885CTSS 880/4885CYP1A2 1665/4885 |
| US-20160083369-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | CXCL12, HPGDS, MCL1 | CTSK 2763/4885CTSS 2739/4885CYP1A2 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.