Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.58 |
| ▸ | CTSS | P25774 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372787 | 1.00 | CTSK (0.58) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12808094 | 1.00 | CTSK (0.58) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23059046 | 0.93 | CTSK (0.60) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1688825 | 0.91 | CTSK (0.59) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15435539 | 0.91 | CTSK (0.59) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12071191 | 0.87 | CYP1A2 (0.64) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30695390 | 0.87 | CTSK (0.49) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12069015 | 0.87 | CYP1A2 (0.64) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12070120 | 0.87 | CYP1A2 (0.64) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25008491 | 0.86 | CTSK (0.49) | CTSKCTSSCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057735-B | Application of bacillus amyloliquefaciens esterase in splitting N-BOC-DL-alpha-methyl aminobutyric acid | 浙江工业大学 | 2021-10-15 | — | — | CN | claimed |
| CN-104531794-B | A kind of preparation method of the aminobutyric acid esters of N BOC D 2 | 浙江工业大学 | 2017-07-28 | — | — | CN | claimed |
| CN-103820416-B | High-stereoselectivity esterolytic enzyme, encoding gene and application of encoding gene | 浙江工业大学 | 2017-04-12 | — | — | CN | claimed |
| CN-104531794-A | Preparation method of N-BOC-D-2-aminobutyrate | UNIV ZHEJIANG TECHNOLOGY | 2015-04-22 | — | — | CN | claimed |
| CN-103820416-A | High-stereoselectivity esterolytic enzyme, encoding gene and application of encoding gene | UNIV ZHEJIANG TECHNOLOGY | 2014-05-28 | — | — | CN | claimed |
| CN-119570870-A | Method for synthesizing L-2-aminobutyric acid and L-2-aminobutanamide hydrochloride and application | 浙江永太科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20230151034-A1 | PEPTIDOMIMETIC N5-METHYL-N2-(NONANOYL-L-LEUCYL)-L-GLUTAMINATE DERIVATIVES, TRIAZASPIRO[4.14]NONADECANE DERIVATIVES AND SIMILAR COMPOUNDS AS INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-18 | — | — | US | disclosed |
| CN-111057735-B | Application of bacillus amyloliquefaciens esterase in splitting N-BOC-DL-alpha-methyl aminobutyric acid | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| US-20210008055-A1 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. | 2021-01-14 | — | — | US | disclosed |
| US-10646505-B2 | DNA-functionalized scaffolds for drug capture applications | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-05-12 | — | — | US | disclosed |
| WO-2019189876-A1 | (CARBOXYLIC ACID-TYPE COMPOUND)-POLYMER CONJUGATE HAVING BIOLOGICAL ACTIVITY, AND METHOD FOR PRODUCING SAME | 生化学工業株式会社 | 2019-10-03 | — | — | WO | disclosed |
| US-20190275024-A1 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-09-12 | — | — | US | disclosed |
| EP-1654260-A2 | 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| US-7022850-B2 | Bicyclicpyrimidones and their use to treat diseases | BRISTOL-MYERS SQUIBB CO. (US) | 2006-04-04 | — | — | US | disclosed |
| US-20050143383-A1 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2005-06-30 | — | — | US | disclosed |
| US-20050107381-A1 | 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders | PFIZER, INC. | 2005-05-19 | — | — | US | disclosed |
| WO-2005011601-A2 | 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS, INC. (US) | 2005-02-10 | — | — | WO | disclosed |
| US-20040242596-A1 | Bicyclicpyrimidones and their use to treat diseases | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-02 | — | — | US | disclosed |
| CN-1433406-A | Benzo [ a ] phenazine-11-amide derivatives and their use as combined topoisomerase I and II inhibitors | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | XENOVA LIMITED (GB) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151034-A1 | PEPTIDOMIMETIC N5-METHYL-N2-(NONANOYL-L-LEUCYL)-L-GLUTAMINATE DERIVATIVES, TRIAZASPIRO[4.14]NONADECANE DERIVATIVES AND SIMILAR COMPOUNDS AS INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | ASNS, GLUL, GNMT | CTSK 1842/4885CTSS 527/4885CYP1A2 4091/4885 |
| US-20210008055-A1 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS | CALCRL, CALCR, CNR2 | CTSK 729/4885CTSS 903/4885CYP1A2 2002/4885 |
| US-20050107381-A1 | 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders | APP, BACE1, SNCA | CTSK 638/4885CTSS 737/4885CYP1A2 1812/4885 |
| US-10646505-B2 | DNA-functionalized scaffolds for drug capture applications | TOP1, TOP2A, DNA2 | CTSK 3378/4885CTSS 2871/4885CYP1A2 2857/4885 |
| US-20050143383-A1 | Pharmaceutical compounds | CHRNA10, OPRM1, SCN10A | CTSK 3439/4885CTSS 3151/4885CYP1A2 184/4885 |
| US-20040242596-A1 | Bicyclicpyrimidones and their use to treat diseases | CCNB1, CCNB2, CCNI | CTSK 1123/4885CTSS 1515/4885CYP1A2 1812/4885 |
| US-20190275024-A1 | PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS | CALCRL, CALCR, CNR2 | CTSK 729/4885CTSS 903/4885CYP1A2 2002/4885 |
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | TOP1, TOP2A, TOP2B | CTSK 3950/4885CTSS 3181/4885CYP1A2 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.