Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F11 | P03951 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637092 | 0.83 | LIPG (0.40) | LPLLIPGESR2F2F11 | |
| SCHEMBL15241491 | 0.83 | HSD11B1 (0.38) | SLC6A2SLC6A4CTSL | |
| SCHEMBL16791658 | 0.83 | CTSL (0.34) | SLC6A2SLC6A4CTSL | |
| SCHEMBL13953460 | 0.82 | LIPG (0.41) | LPLLIPGESR2AAK1F2 | |
| SCHEMBL15436345 | 0.81 | LIPG (0.37) | LPLLIPGESR2AAK1F2 | |
| SCHEMBL13624890 | 0.75 | AAK1 (0.37) | LPLLIPGESR2AAK1F2 | |
| SCHEMBL17120309 | 0.75 | ALOX5 (0.38) | SLC6A2SLC6A4CTSL | |
| SCHEMBL17120320 | 0.75 | ALOX5 (0.38) | SLC6A2SLC6A4CTSL | |
| SCHEMBL15092467 | 0.74 | F11 (0.40) | LPLLIPGESR2AAK1F2 | |
| SCHEMBL15092469 | 0.74 | F11 (0.40) | LPLLIPGESR2AAK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687525-A1 | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 | Boehringer Ingelheim International GmbH (DE) | 2014-01-22 | — | — | EP | disclosed |